Symbol
Name
ID

Gabbr1
gamma-aminobutyric acid type B receptor subunit 1
MGI:1860139

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Addictive alcohol use
Disease(s) Associated with GABBR1	Addictive alcohol use
alcohol dependence

Mouse Phenotypes

behavior/neurological phenotype

impaired behavioral response to xenobiotic

abnormal conditioned taste aversion behavior

impaired passive avoidance behavior

abnormal habituation to a new environment

abnormal object recognition memory

abnormal emotion/affect behavior

decreased depression-related behavior

increased anxiety-related response

hyperresponsive to tactile stimuli

hyporesponsive to tactile stimuli

weakness

abnormal posture

abnormal gait

decreased locomotor activity

increased locomotor activity

abnormal sleep pattern

decreased thermal nociceptive threshold

seizures

audiogenic seizures

clonic seizures

tonic-clonic seizures

absence seizures

sporadic seizures

Availability

Mouse Genotype

Gabbr1^tm1Bet/Gabbr1^tm1Bet

Gabbr1^tm1Dgen/Gabbr1^tm1Dgen

Gabbr1^tm1Pngl/Gabbr1^tm1Pngl

Gabbr1^tm2.1Bet/Gabbr1^tm2.1Bet

Gabbr1^tm2Bet/Gabbr1^tm2Bet

Gabbr1^tm3Bet/Gabbr1^tm3Bet

Gabbr1^tm4Bet/Gabbr1^tm4Bet

Gabbr1^tm1Bet/Gabbr1⁺

Gabbr1^tm2Bet/Gabbr1^tm2Bet
Tg(HCRT-cre)1Stak/0 (conditional)

Gabbr1^tm2Bet/Gabbr1^tm2Bet
Hdc^{tm1.1(icre)Wwis}/Hdc⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23