Gsc RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:46639 Clouthier DE, et al., Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development. 1998 Mar;125(5):813-24
Assay type:	RNA in situ
MGI Accession ID:	MGI:1290060
Gene symbol:	Gsc
Gene name:	goosecoid homeobox

Probe:	Probe 2
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen 8A +/- gsc left: embryonic day 10.5; Ednra^tm1Ywa/Ednra⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch mandibular component	Present	Regionally restricted	8A +/- gsc left	Expression was observed in the medial aspects of both the posterior half of the first mandibular arch and the anterior half of the second arch.
TS17: 2nd branchial arch	Present	Regionally restricted	8A +/- gsc left	Expression was observed in the medial aspects of both the posterior half of the first mandibular arch and the anterior half of the second arch.
TS17: forelimb bud	Present		8A +/- gsc left
TS17: hindlimb bud	Present		8A +/- gsc left
TS17: nasal pit	Present		8A +/- gsc left

Specimen 8A -/- gsc left: embryonic day 10.5; Ednra^tm1Ywa/Ednra^tm1Ywa (more

)

Structure	Level	Image	Note
TS17: forelimb bud	Present	8A -/- gsc left	Expression was not different from the heterozygous embryo in these tissues.
TS17: hindlimb bud	Present	8A -/- gsc left	Expression was not different from the heterozygous embryo in these tissues.
TS17: nasal pit	Present	8A -/- gsc left	Expression was not different from the heterozygous embryo in these tissues.
TS17: 1st branchial arch	Absent	8A -/- gsc left
TS17: 2nd branchial arch	Absent	8A -/- gsc left

Specimen 8A +/- gsc right: embryonic day 10.5; Ednra^tm1Ywa/Ednra⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch mandibular component	Present	Regionally restricted	8A +/- gsc right	Expression was observed in the medial aspects of both the posterior half of the first mandibular arch and the anterior half of the second arch.
TS17: 2nd branchial arch	Present	Regionally restricted	8A +/- gsc right	Expression was observed in the medial aspects of both the posterior half of the first mandibular arch and the anterior half of the second arch.
TS17: forelimb bud	Present		8A +/- gsc right
TS17: hindlimb bud	Present		8A +/- gsc right
TS17: nasal pit	Present		8A +/- gsc right

Specimen 8A -/- gsc right: embryonic day 10.5; Ednra^tm1Ywa/Ednra^tm1Ywa (more

)

Structure	Level	Image	Note
TS17: forelimb bud	Present	8A -/- gsc right	Expression was not different from the heterozygous embryo in these tissues.
TS17: hindlimb bud	Present	8A -/- gsc right	Expression was not different from the heterozygous embryo in these tissues.
TS17: nasal pit	Present	8A -/- gsc right	Expression was not different from the heterozygous embryo in these tissues.
TS17: 1st branchial arch	Absent	8A -/- gsc right
TS17: 2nd branchial arch	Absent	8A -/- gsc right

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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