Gene Expression Image Detail

Reference

Figure

ID

J:46639 Clouthier DE, et al., Development. 1998 Mar;125(5):813-24

8

MGI:1290066

Image

Caption

Pharyngeal arches 1 and 2 are indicated in (A). (B) Proposed model of craniofacial morphogenesis. The interaction of ET-1 (expressed in the epithelium and paraxial mesoderm core of the pharyngeal arches) with the ETa receptor (expressed by the neural crest-derived ectomesenchymal cells) initiates a signalling cascade that likely includes activation of numerous transcription factors including goosecoid. This results in the proper developmental programming of neural crest derivatives in the jaw and neck region. All skeletal elements shown on the right are affected by the ETa mutation. al, alisphenoid.

Copyright

This image is from Clouthier et al., Development 125:813-824 (1998), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A +/- Dlx1 left	MGI:1290059 (Dlx1)
A -/- Dlx1 right	MGI:1290059 (Dlx1)
A +/- gsc left	MGI:1290060 (Gsc)
A -/- gsc left	MGI:1290060 (Gsc)
A +/- Dlx1 right	MGI:1290059 (Dlx1)
A -/- Dlx1 left	MGI:1290059 (Dlx1)
A +/- gsc right	MGI:1290060 (Gsc)
A -/- gsc right	MGI:1290060 (Gsc)