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Cd1d2 Pseudogene Detail
Summary
  • Symbol
    Cd1d2
  • Name
    CD1d2 antigen
  • Synonyms
    CD1.2, Cd1b
Location &
Maps
more
  • Sequence Map
    Chr3:86893875-86896843 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 37.88 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    11
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107675
 polymorphic pseudogene Chr3:86893858-86897087 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027357
 protein coding gene Chr3:87060814-87065002 (+)
A/J MGP_AJ_G0027321
 protein coding gene Chr3:84094924-84097011 (+)
AKR/J MGP_AKRJ_G0027287
 protein coding gene Chr3:86138845-86140248 (+)
BALB/cJ MGP_BALBcJ_G0027330
 protein coding gene Chr3:84196253-84201198 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0027777
 protein coding gene Chr3:90288095-90292721 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025129
 protein coding gene Chr3:79770749-79773642 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0027153
 protein coding gene Chr3:81921453-81922907 (+)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0027172
 protein coding gene Chr3:99598997-99609507 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027834
 protein coding gene Chr3:85904443-85906838 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0026600
 protein coding gene Chr3:86303615-86304893 (-)



Homology
more
  • Human Ortholog
    CD1D, CD1d molecule
  • Vertebrate Orthologs
    8
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CD1D, CD1d molecule
  • Synonyms
    CD1A, R3, R3G1
  • Links
    NCBI Gene ID: 912
    neXtProt AC: NX_P15813
    UniProt: P15813

  • Chr Location
    1q23.1; chr1:158178030-158186427 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CD1D associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    300 phenotype references
Homozygotes for a targeted null mutation ablating both Cd1d1 and Cd1d2 exhibit very few NK1.1-bearing T cells and an impaired interleukin 4 (IL4) response upon systemic T cell activation. Such mice are phenotypically similar to mutants lacking only Cd1d1.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    27
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    765
  • Tissues
    7
  • cDNA Data
    5
  • Literature Summary
    2
Sequences &
Gene Models
less
  • All Sequences
    28
  • RefSeq
    6
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 12480 NCBI Gene Model | MGI Sequence Detail 2969 C57BL/6J ±  kb
transcript NM_007640 RefSeq | MGI Sequence Detail 1246 Not Specified  
polypeptide P11610 UniProt | EBI | MGI Sequence Detail 336 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 6
    cDNA 7

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-11979, MGD-MRK-1835, MGD-MRK-36250
References
more
  • Summaries
    All 340
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 300
  • Earliest
    J:17169 McMichael AJ, et al., A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol. 1979 Mar;9(3):205-10
  • Latest
    J:344733 Amable L, et al., Intrinsic factors and CD1d1 but not CD1d2 expression levels control invariant natural killer T cell subset differentiation. Nat Commun. 2023 Dec 1;14(1):7922
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory