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Zbtb42 Gene Detail
Summary
  • Symbol
    Zbtb42
  • Name
    zinc finger and BTB domain containing 42
  • Synonyms
    Gm5188, simiRP58
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644133
    NCBI Gene: 382639
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:112645262-112649181 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 61.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    72 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644133
 protein coding gene Chr12:112645042-112649181 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020157
 protein coding gene Chr12:115147713-115151084 (+)
A/J MGP_AJ_G0020113
 protein coding gene Chr12:110708734-110712691 (+)
AKR/J MGP_AKRJ_G0020088
 protein coding gene Chr12:113897877-113901832 (+)
BALB/cJ MGP_BALBcJ_G0020098
 protein coding gene Chr12:111153059-111156980 (+)
C3H/HeJ MGP_C3HHeJ_G0019900
 protein coding gene Chr12:114407417-114411372 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020543
 protein coding gene Chr12:118706066-118711910 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018157
 protein coding gene Chr12:107139411-107143378 (+)
CAST/EiJ MGP_CASTEiJ_G0019440
 protein coding gene Chr12:109255005-109258962 (+)
CBA/J MGP_CBAJ_G0019867
 protein coding gene Chr12:123242094-123246049 (+)
DBA/2J MGP_DBA2J_G0019984
 protein coding gene Chr12:110187617-110191553 (+)
FVB/NJ MGP_FVBNJ_G0019969
 protein coding gene Chr12:109013707-109017663 (+)
LP/J MGP_LPJ_G0020058
 protein coding gene Chr12:114975058-114980123 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020007
 protein coding gene Chr12:126327382-126332709 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020572
 protein coding gene Chr12:113422750-113429551 (+)
PWK/PhJ MGP_PWKPhJ_G0019202
 protein coding gene Chr12:104845911-104849982 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019006
 protein coding gene Chr12:107585325-107589247 (+)
WSB/EiJ MGP_WSBEiJ_G0019500
 protein coding gene Chr12:114329702-114333660 (+)



Homology
more
  • Human Ortholog
    ZBTB42, zinc finger and BTB domain containing 42
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZBTB42, zinc finger and BTB domain containing 42
  • Synonyms
    LCCS6, ZNF925
  • Links
    NCBI Gene ID: 100128927
    neXtProt AC: NX_B2RXF5
    UniProt: B2RXF5

  • Chr Location
    14q32.33; chr14:104800554-104804712 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ZBTB42 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    22
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037638 Ensembl Gene Model | MGI Sequence Detail 3920 C57BL/6J ±  kb
    transcript ENSMUST00000169593 Ensembl | MGI Sequence Detail 3478 Not Applicable  
    polypeptide ENSMUSP00000133152 Ensembl | MGI Sequence Detail 420 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 22

      Microarray probesets 1
    References
    more
    • Summaries
      All 23
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 2
    • Earliest
      J:91257 Gray PA, et al., Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
    • Latest
      J:308922 Medeiros de Araujo JA, et al., ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex. Development. 2021 Aug 15;148(16):dev196642
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory