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Mphosph9 Gene Detail
Summary
  • Symbol
    Mphosph9
  • Name
    M-phase phosphoprotein 9
  • Synonyms
    4930548D04Rik, 9630025B04Rik, B930097C17Rik, MPP-9, MPP9
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443138
    NCBI Gene: 269702
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:124389022-124466001 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 63.47 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1995 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443138
 protein coding gene Chr5:124389022-124466035 (-)
129S1/SvImJ ENSMUSG00200028118
 protein coding gene Chr5:118112082-118188769 (-)
A/J ENSMUSG00195012163
 protein coding gene Chr5:117633638-117710333 (-)
AKR/J ENSMUSG00220040248
 protein coding gene Chr5:117143312-117220303 (-)
BALB/cJ ENSMUSG00180035976
 protein coding gene Chr5:117748563-117825252 (-)
C3H/HeJ ENSMUSG00175024493
 protein coding gene Chr5:119749545-119826526 (-)
C57BL/6NJ ENSMUSG00215014926
 protein coding gene Chr5:117798135-117875155 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027746
 protein coding gene Chr5:117253676-117328889 (-)
CAST/EiJ ENSTCUG00005039414
 protein coding gene Chr5:117034122-117107278 (-)
CBA/J ENSMUSG00210009633
 protein coding gene Chr5:118500506-118577489 (-)
DBA/2J ENSMUSG00185006641
 protein coding gene Chr5:121551567-121628548 (-)
FVB/NJ ENSMUSG00205040948
 protein coding gene Chr5:117426003-117503028 (-)
JF1/MsJ ENSUMUG00000035433
 protein coding gene Chr5:124410136-124488660 (-)
LP/J ENSMUSG00230044941
 protein coding gene Chr5:125633986-125710670 (-)
NOD/ShiLtJ ENSMUSG00190039469
 protein coding gene Chr5:117425939-117502919 (-)
NZO/HlLtJ ENSMUSG00225013459
 protein coding gene Chr5:133330925-133407938 (-)
PWK/PhJ ENSLUMG00010040962
 protein coding gene Chr5:116313092-116389994 (-)
SPRET/EiJ ENSMSPG00010043892
 protein coding gene Chr5:119615354-119687651 (-)
WSB/EiJ ENSIUOG00005014961
 protein coding gene Chr5:120125853-120202841 (-)



Homology
more
  • Human Ortholog
    MPHOSPH9, M-phase phosphoprotein 9
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MPHOSPH9, M-phase phosphoprotein 9
  • Synonyms
    MPP-9, MPP9
  • Links
    NCBI Gene ID: 10198
    UniProt: Q99550

  • Chr Location
    12q24.31; chr12:123152320-123244014 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MPHOSPH9 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit a twisted body axis at midgestation, decreased weight and an increased percentage of ciliated cells in the proximal and distal tubules.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    1
  • cDNA Data
    55
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 269702 NCBI Gene Model | MGI Sequence Detail 76980 C57BL/6J ±  kb
transcript NM_001277867 RefSeq | MGI Sequence Detail 7754 C57BL/6  
polypeptide A6H5Y1 UniProt | EBI | MGI Sequence Detail 1114 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 56
    cDNA 55
    Primer pair 1

    Microarray probesets 11
Other
Accession IDs
less
MGI:1922504, MGI:2141191, MGI:2141219, MGI:3035377
References
more
  • Summaries
    All 51
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 18
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory