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TT11 Probe Detail
Nucleotide
Probe/Clone
  • Name
    TT11
  • Sequence Type
    cDNA
  • ID
    MGI:14842
  • Region Covered
    encodes 5' untranslated region, Tcra-V1, Tcra-J, Tcra-C gene segments and 5' untranslated region
  • Vector Type
    Phage
  • Insert Site
    EcoRI
  • Insert Size
    ~1.6 kb
  • Note
    The Tcra-V1 gene segment encoded by TT11 was contributed by the parent T-cell tumor BW5147 which is of AKR orgin.
Source
  • Species
    mouse, laboratory
  • Strain
    AKR
  • Tissue
    helper T-lymphocyte
  • Cell Line
    hybridoma cell line 2B4
Genes
Tcra-J T cell receptor alpha, joining region
Tcra-V1 T cell receptor alpha, variable 1
Trac T cell receptor alpha constant
Polymorphisms
J:7626 Chien Y, et al., Nature. 1984 Nov 1-7;312(5989):31-5
Notes: A ~600 bp EcoRI/EcoRV fragment was isolated from the 5'-portion of TT11 and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
BglII Tcra-V1 a multiple BALB/c
b multiple C57BL/6
HindIII Tcra-V1 a multiple BALB/c
b multiple AKR
c multiple B10.A-H2a
XbaII Tcra-V1 a multiple BALB/c
b multiple C57BL/6
References
J:7626 Chien Y, et al., A third type of murine T-cell receptor gene. Nature. 1984 Nov 1-7;312(5989):31-5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory