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Tcra-J Complex/Cluster/Region Detail
Summary
  • Symbol
    Tcra-J
  • Name
    T cell receptor alpha, joining region
  • Synonyms
    Jalpha281
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:98555
    NCBI Gene: 21475
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 14, Syntenic
  • Mapping Data
    1 experiment
Human Diseases
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  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    44 phenotypes from 7 alleles in 8 genetic backgrounds
    10 phenotypes from multigenic genotypes
    1 images
    334 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes with mutations in this locus have aberrant recombination of the Tcra gene segments that affects expression of the T-cell receptor.
Expression
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  • Literature Summary
    1
  • Other Mouse Links
    GEO
Sequences &
Gene Models
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  • All Sequences
    3
Representative SequencesLengthStrain/SpeciesFlank
genomic M38099 GenBank | ENA | DDBJ | MGI Sequence Detail 701 B10.BR-H2 H2-T18/SgSnJ ±  kb
For the selected sequence
Molecular
Reagents
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  • All nucleic 131
    Genomic 57
    cDNA 69
    Other 5
Other
Accession IDs
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MGD-MRK-14847
References
more
  • Summaries
    All 369
    Developmental Gene Expression 1
    Diseases 1
    Phenotypes 334
  • Earliest
    J:7626 Chien Y, et al., A third type of murine T-cell receptor gene. Nature. 1984 Nov 1-7;312(5989):31-5
  • Latest
    J:346308 Robin A, et al., Early activation and recruitment of invariant natural killer T cells during liver ischemia-reperfusion: the major role of the alarmin interleukin-33. Front Immunol. 2023;14:1099529
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/07/2026
MGI 6.24 		The Jackson Laboratory