pHDS58 Probe Detail MGI Mouse MGI:10208

pHDS58 Probe Detail

Name

pHDS58
Sequence Type

cDNA
ID

MGI:10208
Region Covered

encodes Tcra-V3, Tcra-J(2c), Tcra-C gene segments, as well as 5'/3'-untranslated regions
Insert Site

PstI
Insert Size

1372 bp

Species

mouse, laboratory
Strain

BALB.B
Tissue

cytotoxic T-lymphocyte
Cell Line

2C

Tcra-J	T cell receptor alpha, joining region
Tcra-V3	T cell receptor alpha, variable 3
Trac	T cell receptor alpha constant

J:8483 Berman JW, et al., Immunogenetics. 1986;24(5):328-30

Endonuclease	Gene	Allele	Fragments	Strains
EcoRI	Tcra-V3	b	~18,~13,9,6.2,3.9,2.2, .9kb	B10.D2-Hc⁰ H2^d H2-T18^c/oSnJ, C57BL/6J, C57BL/10J, C57BLKS, C57BR/cdJ, C57L/J, C58/J
		c	20,15,9,6.2,3.9,2.2kb	129P3/J, A/J, AKR/J, B6By.C-H8^c, BALB/c, C3H/J, RF/J, SJL/J
		d	~20,~15,6.2,~5,3.9,2.2kb	B10.D2/(57N)Sn, DBA/2J

J:10336 Crosby JL, et al., Genomics. 1990 Feb;6(2):252-9

Endonuclease	Gene	Allele	Fragments	Strains
HindIII	Tcra	b	absent	C57BL/6J
HindIII	Tcra	s	2.3,9.0,9.8,20.0kb	M. spretus

J:10663 Eicher EM, et al., Genetics. 1990 Jun;125(2):431-46

Endonuclease	Gene	Allele	Fragments	Strains
EcoRI	Tcra	n	11.1,2.2kb	NZB
EcoRI	Tcra	s	absent	SM

J:7627 Saito H, et al., A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature. 1984 Nov 1-7;312(5989):36-40

J:7727 Kranz DM, et al., Chromosomal locations of the murine T-cell receptor alpha-chain gene and the T-cell gamma gene. Science. 1985 Feb 22;227(4689):941-5

J:7998 Hayday AC, et al., Unusual organization and diversity of T-cell receptor alpha-chain genes. Nature. 1985 Aug 29-Sep 4;316(6031):828-32

J:8483 Berman JW, et al., Restriction length polymorphism in the variable region of the Tcr locus linked to histocompatibility antigen H-8 on murine chromosome 14. Immunogenetics. 1986;24(5):328-30

J:10336 Crosby JL, et al., A complex of serine protease genes expressed preferentially in cytotoxic T-lymphocytes is closely linked to the T-cell receptor alpha- and delta-chain genes on mouse chromosome 14. Genomics. 1990 Feb;6(2):252-9

J:10663 Eicher EM, et al., The NXSM recombinant inbred strains of mice: genetic profile for 58 loci including the Mtv proviral loci. Genetics. 1990 Jun;125(2):431-46

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23