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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lamb2
laminin, beta 2
MGI:99916
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Col4a3tm1Jhm/Col4a3tm1Jhm
Lamb2em1Jhm/Lamb2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J 		abnormal kidney morphology J:280129
abnormal renal glomerulus basement membrane morphology J:280129
albuminuria J:280129
glomerular crescent J:280129
glomerulosclerosis J:280129
increased blood urea nitrogen level J:280129
kidney failure J:280129
podocyte foot process effacement J:280129
premature death J:280129
Col4a3tm1Jhm/Col4a3tm1Jhm
Lamb2em1Jhm/Lamb2em1Jhm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J 		abnormal renal glomerulus basement membrane morphology J:280129
glomerulosclerosis J:280129
podocyte foot process effacement J:280129
Col4a5tm1Yseg/Col4a5+
Lamb2em1Jhm/Lamb2+
involves: 129X1/SvJ * C57BL/6J * CBA/J 		abnormal kidney morphology J:280129
albuminuria J:280129
glomerulosclerosis J:280129
Fgfr2tm1Dor/Fgfr2tm1Dor
Lamb2tm1Jrs/Lamb2tm1Jrs
Tg(Mnx1-cre)1Jrs/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal synaptic vesicle clustering J:126496
Lamb2tm1Jrs/Lamb2tm1Jrs
Lamc3tm1.1Wjbr/Lamc3tm1.1Wjbr
B6.129-Lamc3tm1.1Wjbr Lamb2tm1Jrs 		abnormal amacrine cell morphology J:169656
abnormal eye physiology J:169656
abnormal Muller cell morphology J:169656
abnormal retina development J:169656
abnormal retina morphology J:169656
decreased amacrine cell number J:169656
Lamb2tm1Jrs/Lamb2tm1Jrs
Tg(Ckm-Lamb2)1Jhm/0
Tg(Nphs1-Lamb2*S83R)#Jhm/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		normal homeostasis/metabolism phenotype J:280129
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory