Otp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Otp
orthopedia homeobox
MGI:99835

30 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Otp^M1H/Otp⁺ C3H.Cg-Otp^M1H	abnormal energy homeostasis	J:251771
	abnormal fat pad morphology	J:251771
	decreased body weight	J:251771
	decreased bone mineral density	J:251771
	impaired glucose tolerance	J:251771
	increased body fat mass	J:251771
	increased body length	J:251771
	increased circulating insulin level	J:251771
	increased circulating leptin level	J:251771
	increased energy expenditure	J:251771
	increased food intake	J:251771
	increased lean body mass	J:251771
	increased white adipose tissue amount	J:251771
	insulin resistance	J:251771
	obese	J:251771
Otp^M1H/Otp^M1H C3H.Cg-Otp^M1H	preweaning lethality, complete penetrance	J:251771
Otp^M1H/Otp^tm1Asim involves: 129P2/OlaHsd * C3H/HeH * C57BL/6J	preweaning lethality, complete penetrance	J:251771
Otp^tm1Asim/Otp⁺ C3H.129P2(B6)-Otp^tm1Asim	impaired glucose tolerance	J:251771
	increased body fat mass	J:251771
	increased circulating leptin level	J:251771
	increased lean body mass	J:251771
	insulin resistance	J:251771
	obese	J:251771
Otp^tm1Asim/Otp^tm1Asim involves: 129P2/OlaHsd	abnormal dopaminergic neuron morphology	J:122105
Otp^{tm1b(EUCOMM)Wtsi}/Otp⁺ C57BL/6N-Otp^{tm1b(EUCOMM)Wtsi}/H	decreased mean platelet volume	J:211773
	increased circulating iron level	J:211773
Otp^{tm1b(EUCOMM)Wtsi}/Otp^{tm1b(EUCOMM)Wtsi} C57BL/6N-Otp^{tm1b(EUCOMM)Wtsi}/H	preweaning lethality, complete penetrance	J:211773
Otp^tm1Tlu/Otp^tm1Tlu either: 129/Sv-Otp^tm1Tlu or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	abnormal diencephalon morphology	J:65759
	abnormal hypothalamus morphology	J:65759
	abnormal hypothalamus physiology	J:65759
	abnormal neurohypophysis median eminence morphology	J:65759
	abnormal neurohypophysis morphology	J:65759
	abnormal paraventricular hypothalamic nucleus morphology	J:65759
	abnormal supraoptic nucleus morphology	J:65759
	abnormal third ventricle morphology	J:65759
	decreased body size	J:65759
	decreased body weight	J:65759
	decreased brain size	J:65759
	postnatal lethality, complete penetrance	J:65759

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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