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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Drd1
dopamine receptor D1
MGI:99578
73 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Drd1tm1(cre)Rpa/Drd1+
Gad1tm1Rpa/Gad1tm1.1Rpa
involves: 129S4/SvJaeSor * C57BL/6
abnormal motor coordination/balance J:138586
normal behavior/neurological phenotype J:138586
decreased grip strength J:138586
limb grasping J:138586
Drd1tm1.1(IL2RA/Venus)Koba/Drd1+
B6.129S6-Drd1tm1.1(IL2RA/Venus)Koba
abnormal neuron morphology J:184374
abnormal operant conditioning behavior J:184374
normal behavior/neurological phenotype J:184374
Drd1tm1Jcd/Drd1+
Drd2tm1Ebo/Drd2tm1Ebo
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
normal mortality/aging J:91781
Drd1tm1Jcd/Drd1tm1Jcd
Drd2tm1Ebo/Drd2+
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
abnormal duodenum morphology J:91781
abnormal eating behavior J:91781
abnormal stomach morphology J:91781
gastrointestinal hemorrhage J:91781
intestinal ulcer J:91781
postnatal growth retardation J:91781
premature death J:91781
small intestinal inflammation J:91781
Drd1tm1Jcd/Drd1tm1Jcd
Drd2tm1Ebo/Drd2tm1Ebo
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
abnormal digestive system development J:91781
abnormal digestive system physiology J:91781
abnormal hypothalamus physiology J:91781
abnormal intestinal smooth muscle morphology J:91781
abnormal intestine morphology J:91781
absent gastric milk in neonates J:91781
aphagia J:91781
decreased body size J:91781
decreased locomotor activity J:91781
gastrointestinal hemorrhage J:91781
normal nervous system phenotype J:91781
postnatal growth retardation J:91781
postnatal lethality, complete penetrance J:91781
Drd1tm1Jcd/Drd1tm1Jcd
Drd3tm1Dac/Drd3tm1Dac
involves: 129S4/SvJae * C57BL/6
abnormal spatial learning J:102600
normal behavior/neurological phenotype J:102600
behavioral despair J:102600
decreased body size J:102600
decreased locomotor activity J:102600
decreased vertical activity J:102600
impaired coordination J:102600
impaired swimming J:102600
increased thigmotaxis J:102600
Drd1tm2.1Stl/Drd1tm2.1Stl
Drd5tm1.1Stl/Drd5tm1.1Stl
Tg(Camk2a-cre)T29-1Stl/0
involves: BALB/c * C57BL * C57BL/6
abnormal long-term potentiation J:211355
decreased fear-related response J:211355
impaired contextual conditioning behavior J:211355
Drd1tm2Jcd/Drd1+
either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * CD-1)
no abnormal phenotype detected J:120582
Drd1tm2Jcd/Drd1+
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S4/SvJae * BALB/c * CD-1 * FVB/N
abnormal forebrain morphology J:120582
abnormal hippocampus morphology J:120582
abnormal nervous system physiology J:120582
abnormal posture J:120582
abnormal striatum morphology J:120582
bradykinesia J:120582
decreased brain size J:120582
decreased brain weight J:120582
decreased forebrain size J:120582
decreased forebrain volume J:120582
decreased pulmonary respiratory rate J:120582
dystonia J:120582
gliosis J:120582
impaired balance J:120582
impaired righting response J:120582
myoclonus J:120582
postnatal lethality, complete penetrance J:120582
Drd1tm2Jcd/Drd1+
Tg(Camk2a-cre)2Gsc/0
involves: 129S4/SvJae * FVB/N
abnormal brain wave pattern J:120070
abnormal cerebral cortex morphology J:120070
abnormal dentate gyrus morphology J:120070
abnormal forebrain morphology J:120070
abnormal microglial cell physiology J:120070
abnormal nervous system morphology J:120070
abnormal nervous system physiology J:120070
astrocytosis J:120070
decreased body weight J:120070
decreased brain size J:120070
decreased brain weight J:120070
decreased hippocampus volume J:120070
decreased striatum size J:120070
dystonia J:120070
enlarged lateral ventricles J:120070
increased locomotor activity J:120070
increased vertical activity J:120070
limb grasping J:120070
seizures J:120070
striatum atrophy J:120070
trunk curl J:120070
Or8a1tm41(Drd1)Mom/Or8a1tm41(Drd1)Mom
B6;129P2-Or8a1tm41(Drd1)Mom/MomJ
abnormal olfactory sensory neuron morphology J:260975
decreased olfactory sensory neuron number J:260975
Prkar2btm3Gsm/Prkar2btm2Gsm
Drd1tm1(cre)Rpa/Drd1+
involves: C57BL/6
normal adipose tissue phenotype J:196157
normal growth/size/body region phenotype J:196157
normal homeostasis/metabolism phenotype J:196157
hyperactivity J:196157

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory