Drd1^tm1(cre)Rpa
Targeted Allele Detail

Summary

• Symbol: Drd1^tm1(cre)Rpa
• Name: dopamine receptor D1; targeted mutation 1, Richard D Palmiter
• MGI ID: MGI:3527153
• Synonyms: Dr1-Cre, Drd1a-Cre
• Gene: Drd1 Location: Chr13:54205202-54209677 bp, - strand Genetic Position: Chr13, 28.4 cM
• Alliance: Drd1^tm1(cre)Rpa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138586
• Parent Cell Line: AK18.1 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Drd1^tm1(cre)Rpa expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Drd1 (MGI:99578)

• Mutation details: A cassette containing a cre gene with a nuclear localization signal and an IRES-EGFP was inserted into the open reading frame. (J:138586)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Drd1 (mouse) Summary of all recombinase alleles driven by Drd1. Comparative matrix view of recombinase activities Alliance mouse Drd1 gene page

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Drd1 Mutation: 68 strains or lines available

References

• Original: J:138586 Heusner CL, et al., Deletion of GAD67 in dopamine receptor-1 expressing cells causes specific motor deficits. Genesis. 2008 Jul;46(7):357-67
• All: 14 reference(s)