Acsm3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Acsm3
acyl-CoA synthetase medium-chain family member 3
MGI:99538

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Acsm3^em1Wayb/Acsm3^em1Wayb involves: C57BL/6J	abnormal hepatocyte mitochondrial morphology	J:365449
	abnormal hepatocyte physiology	J:365449
	abnormal mitochondrial physiology	J:365449
	decreased body weight	J:365449
	decreased cellular ATP level	J:365449
	decreased food intake	J:365449
	decreased liver enzyme/coenzyme level	J:365449
	decreased oxygen consumption	J:365449
	decreased respiratory quotient	J:365449
	hepatic steatosis	J:365449
	impaired glucose tolerance	J:365449
	increased circulating alanine transaminase level	J:365449
	increased circulating aspartate transaminase level	J:365449
	increased circulating cholesterol level	J:365449
	increased circulating free fatty acids level	J:365449
	increased circulating HDL cholesterol level	J:365449
	increased circulating LDL cholesterol level	J:365449
	increased circulating triglyceride level	J:365449
	increased liver cholesterol level	J:365449
	increased liver free fatty acids level	J:365449
	increased liver triglyceride level	J:365449
	increased liver weight	J:365449
	insulin resistance	J:365449
	liver degeneration	J:365449
	oxidative stress	J:365449
Acsm3^tm1Njs/Acsm3^tm1Njs involves: 129/Sv * 129P2/OlaHsd	no abnormal phenotype detected	J:103031

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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