Zscan21 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zscan21
zinc finger and SCAN domain containing 21
MGI:99182

26 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Stra8-icre)1Reb/0 Zscan21^tm1.1Jiwa/Zscan21^tm1.1Jiwa involves: FVB/NJ	abnormal double-strand DNA break repair	J:237046
	abnormal spermatid morphology	J:237046
	abnormal spermatocyte morphology	J:237046
	abnormal X-Y chromosome synapsis during male meiosis	J:237046
	arrest of male meiosis	J:237046
	decreased testis weight	J:237046
	male infertility	J:237046
Tg(Zfp38)A4Htz/0 involves: C57BL/6 * CBA	alopecia	J:56546
Tg(Zfp38)A4Htz/0 involves: C57BL/6 * CBA	progressive hair loss	J:56546
Tg(Zfp38)D1Htz/0 involves: C57BL/6 * CBA	abnormal cerebellar granule layer morphology	J:56546
	abnormal cerebellum fissure morphology	J:56546
	abnormal dermal layer morphology	J:56546
	abnormal hair follicle morphology	J:56546
	abnormal hair shaft morphology	J:56546
	abnormal skin development	J:56546
	accelerated formation of intralobular fissures	J:56546
	alopecia	J:56546
	enlarged cerebellum	J:56546
	epithelioid cyst	J:56546
	increased cerebellar granule cell number	J:56546
	progressive hair loss	J:56546
Zscan21^tm1Htz/Zscan21^tm1Htz Not Specified	no abnormal phenotype detected	J:56546
Zscan21^{tm2b(EUCOMM)Wtsi}/Zscan21⁺ C57BL/6N-Zscan21^{tm2b(EUCOMM)Wtsi}/Bay	abnormal skin coloration	J:211773
	decreased respiratory quotient	J:211773
	decreased total retina thickness	J:211773
Zscan21^{tm2b(EUCOMM)Wtsi}/Zscan21^{tm2b(EUCOMM)Wtsi} C57BL/6N-Zscan21^{tm2b(EUCOMM)Wtsi}/Bay	abnormal retina inner nuclear layer morphology	J:211773
	decreased total retina thickness	J:211773
	female infertility	J:211773
	male infertility	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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