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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Twist1
twist basic helix-loop-helix transcription factor 1
MGI:98872
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Id1tm1Zhu/Id1+
Id3tm1Zhu/Id3+
Twist1tm1Bhr/Twist1+
involves: 129S1/Sv * 129S4/SvJaeSor * 129S7/SvEvBrd 		premature cranial suture closure J:108218
Id1tm1Zhu/Id1tm1Zhu
Id3tm1Zhu/Id3+
Twist1tm1Bhr/Twist1+
involves: 129S1/Sv * 129S4/SvJaeSor * 129S7/SvEvBrd 		normal skeleton phenotype J:108218
Id1tm1Zhu/Id1tm1Zhu
Twist1tm1Bhr/Twist1+
involves: 129S1/Sv * 129S7/SvEvBrd 		premature cranial suture closure J:108218
Msx2tm1Rilm/Msx2+
Twist1tm1Bhr/Twist1+
involves: 129S4/SvJae * 129S7/SvEvBrd * BALB/c * C57BL/6 		frontal bone foramen J:87044
polydactyly J:87044
Runx2tm1Mjo/Runx2+
Twist1tm1Bhr/Twist1+
involves: 129S7/SvEvBrd * C57BL/6 		clavicle hypoplasia J:90056
normal craniofacial phenotype J:90056
Tg(CAG-cat,-Twist1)1Dbsp/0
Tg(Col2a1-cre)1Bhr/0
involves: C57BL/6 * FVB * SJL 		abnormal long bone epiphyseal plate morphology J:178268
abnormal long bone epiphyseal plate proliferative zone J:178268
abnormal ossification involved in bone maturation J:178268
decreased body size J:178268
decreased body weight J:178268
decreased bone trabecula number J:178268
decreased trabecular bone thickness J:178268
decreased trabecular bone volume J:178268
increased width of hypertrophic chondrocyte zone J:178268
short limbs J:178268
Twist1tm1Bhr/Twist1+
Twist2tm1(cre)Dor/Twist2+
involves: 129/Sv * 129X1/SvJ 		abnormal skeletal muscle morphology J:81485
cachexia J:81485
neonatal lethality, incomplete penetrance J:81485
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory