Tph1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tph1
tryptophan hydroxylase 1
MGI:98796

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
\Htr1b^tm1Rhn/\Htr1b⁺ \Tph1^tm1Kry/\Tph1⁺ \Tg(Vil1-cre)20Syr/0 involves: 129S2/SvPas * C57BL/6 * DBA/2	increased bone mass	J:146078
\Lrp5^tm1Kry/\Lrp5^tm1Kry \Tph1^tm1Kry/\Tph1⁺ \Tg(Vil1-cre)20Syr/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2	normal skeleton phenotype	J:146078
\Tph1^tm2Lex/\Tph1^tm2Lex \Tph2^tm1Lex/\Tph2^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal emotion/affect behavior	J:144582
	abnormal response to novel object	J:144582
	decreased body length	J:144582
	decreased body weight	J:144582
	decreased percent body fat/body weight	J:144582
	decreased serotonin level	J:144582
	decreased thermal nociceptive threshold	J:144582

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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