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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tgm2
transglutaminase 2, C polypeptide
MGI:98731
30 phenotypes from 4 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tgm2tm1.1Rmgr/Tgm2tm1.1Rmgr
129(B6)-Tgm2tm1.1Rmgr
normal growth/size/body region phenotype J:200838
normal homeostasis/metabolism phenotype J:200838
Tgm2tm1.1Rmgr/Tgm2tm1.1Rmgr
B6.129S1-Tgm2tm1.1Rmgr
normal homeostasis/metabolism phenotype J:200838
increased body weight J:200838
Tgm2tm1.1Rmgr/Tgm2tm1.1Rmgr
involves: 129S1/SvImJ * C57BL/6
abnormal cell adhesion J:95130
abnormal T cell physiology J:95130
Tgm2tm1Gml/Tgm2tm1Gml
involves: 129X1/SvJ * C57BL/6
decreased circulating insulin level J:78633
decreased erythrocyte cell number J:75566
decreased hematocrit J:75566
hyperglycemia J:78633
impaired glucose tolerance J:78633
increased insulin sensitivity J:78633
increased physiological sensitivity to xenobiotic J:82489
increased susceptibility to induced morbidity/mortality J:82489
Tgm2tm1Gml/Tgm2tm1Gml
involves: C57BL/6
abnormal cardiovascular system physiology J:126414
abnormal mitochondrial ATP synthesis coupled electron transport J:126414, J:131975
abnormal response to cardiac infarction J:126414
normal cardiovascular system phenotype J:131975
decreased susceptibility to endotoxin shock J:131975
decreased susceptibility to induced morbidity/mortality J:131975
disorganized myocardium J:131975
normal immune system phenotype J:131975
increased macrophage cell number J:131975
increased myocardial infarct size J:126414
increased tumor growth/size J:126131
premature death J:126131
normal renal/urinary system phenotype J:131975
ventricular fibrillation J:126414
Tgm2tm1Gml/Tgm2tm1Gml
involves: C57BL/6 * DBA/1LacJ
abnormal thymus morphology J:132254
normal homeostasis/metabolism phenotype J:132254
impaired macrophage phagocytosis J:132254
Tgm2tm1Syki/Tgm2tm1Syki
involves: 129P2/OlaHsd * C57BL/6
decreased susceptibility to injury J:167049
Tgm2tm2.1Rmgr/Tgm2tm2.1Rmgr
involves: C57BL/6 * C57BL/6J
normal homeostasis/metabolism phenotype J:200838

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory