Sox5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sox5
SRY (sex determining region Y)-box 5
MGI:98367

17 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sox5^tm1.1Tlu/Sox5^tm1.1Tlu either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)	no abnormal phenotype detected	J:183576
Sox5^tm1Vlf/Sox5^tm1Vlf involves: 129S7/SvEvBrd * C57BL/6	abnormal bone mineralization	J:80666
	abnormal neurocranium morphology	J:80666
	abnormal sternum morphology	J:80666
	abnormal thoracic cage shape	J:80666
	cleft secondary palate	J:80666
	failure of palatal shelf elevation	J:80666
	neonatal lethality, complete penetrance	J:80666
	pectus excavatum	J:80666
	respiratory distress	J:80666
	respiratory failure	J:80666
	short ribs	J:80666
	short sternum	J:80666
Sox5^tm2.1Vlf/Sox5^tm2.1Vlf involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J * SJL	abnormal cervical vertebrae morphology	J:137217
	abnormal sternum ossification	J:137217
	abnormal thoracic cage shape	J:137217
	cleft secondary palate	J:137217
	neonatal lethality, complete penetrance	J:137217
	palatal shelves fail to meet at midline	J:137217
Sox5^tm2Vlf/Sox5^tm2Vlf involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL	no abnormal phenotype detected	J:137217
Sox5^tm2Vlf/Sox5^tm2Vlf Tg(Prrx1-cre)1Cjt/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL	no abnormal phenotype detected	J:137217
Sox5^{Tn(sb-lacZ,GFP)IF2.OR123Jtak}/Sox5^{Tn(sb-lacZ,GFP)IF2.OR123Jtak} involves: C3H * C57BL/6 * DBA/2 * ICR	cyanosis	J:104043
	neonatal lethality, complete penetrance	J:104043
	respiratory distress	J:104043

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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