Sox5^tm1.1Tlu
Targeted Allele Detail

Summary

• Symbol: Sox5^tm1.1Tlu
• Name: SRY (sex determining region Y)-box 5; targeted mutation 1.1, Thomas Lufkin
• MGI ID: MGI:5319181
• Synonyms: Sox5^HA
• Gene: Sox5 Location: Chr6:143774151-144727703 bp, - strand Genetic Position: Chr6, 76.14 cM
• Alliance: Sox5^tm1.1Tlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183576
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A floxed neo cassette and HA tag were inserted upstream of the translation start site. Cre-mediated recombination removed the neo cassette. (J:183576)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox5 Mutation: 44 strains or lines available

References

• Original: J:183576 Lee WJ, et al., Endogenous tagging of the murine transcription factor Sox5 with hemaglutinin for functional studies. Transgenic Res. 2012 Apr;21(2):293-301
• All: 1 reference(s)