24 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Sod2tm1(rtTA*M2,tetO)Jsg/Sod2tm1(rtTA*M2,tetO)Jsg involves: 129S6/SvEvTac * C57BL/6	abnormal double-strand DNA break repair	J:209713
	abnormal redox activity	J:209713
	increased cell death	J:209713
	increased cellular sensitivity to gamma-irradiation	J:209713
Sod2tm1(tetO-Sod2)Evbo/Sod2+ involves: 129S4/SvJae * C57BL/6	abnormal heart left ventricle morphology	J:162190
	cardiac fibrosis	J:162190
	decreased ventricle muscle contractility	J:162190
	increased cardiomyocyte apoptosis	J:162190
	increased myocardial fiber size	J:162190
	increased physiological sensitivity to xenobiotic	J:162190
	myocardium necrosis	J:162190
Sod2tm1(tetO-Sod2)Evbo/Sod2tm1(tetO-Sod2)Evbo involves: 129S4/SvJae * C57BL/6	decreased body size	J:162190
	decreased locomotor activity	J:162190
	impaired balance	J:162190
	increased cardiomyocyte apoptosis	J:162190
	oxidative stress	J:162190
	postnatal lethality, complete penetrance	J:162190
Sod2tm1Cje/Sod2+ Tg(SOD1*G93A)1Gur/0 involves: C57BL/6 * CD-1 * SJL	abnormal motor neuron morphology	J:62381
	decreased neuron number	J:62381
	decreased spinal cord size	J:62381
	decreased spinal cord ventral horn cell number	J:62381
	decreased substantia nigra size	J:62381
	impaired coordination	J:62381
	premature death	J:62381
Sod2tm1Cje/Sod2tm1Cje SvtmsC57BL/6J/SvtmsC57BL/6J involves: C57BL/6J * DBA/2J	postnatal lethality, complete penetrance	J:108213
Sod2tm1Cje/Sod2tm1Cje SvtmsC57BL/6J/SvtmsDBA/2J involves: C57BL/6J * DBA/2J	normal mortality/aging	J:108213