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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rheb
Ras homolog enriched in brain
MGI:97912
10 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atg5tm1Myok/Atg5tm1Myok
Rhebtm1.1Otsu/Rhebtm1.1Otsu
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * C57BL/6J * FVB/N 		postnatal lethality, complete penetrance J:197831
Eif4ebp1tm1Nso/Eif4ebp1tm1Nso
Rhebtm1.1Otsu/Rhebtm1.1Otsu
Tg(Myh6-cre)2182Mds/0
involves: 129 * C57BL/6J * FVB/N 		normal cardiovascular system phenotype J:197831
postnatal lethality, incomplete penetrance J:197831
Gt(ROSA)26Sortm1(CAG-Rheb*)Pfw/Gt(ROSA)26Sor+
Rhebtm1Pfw/Rhebtm1Pfw
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL 		normal nervous system phenotype J:168571
Rhebtm1.1Pfw/Rheb+
Rhebl1tm1.1Pfw/Rhebl1tm1.1Pfw
involves: C57BL/6 		normal mortality/aging J:168571
Rhebtm1.1Pfw/Rhebtm1.1Pfw
Rhebl1tm1.1Pfw/Rhebl1tm1.1Pfw
involves: C57BL/6 		embryonic lethality during organogenesis, complete penetrance J:168571
Rhebtm1.1Yelg/Rheb+
Tsc1tm1Chdl/Tsc1tm1Chdl
B6.129P2-Tsc1tm1Chdl Rhebtm1.1Yelg 		decreased fetal size J:170999
fetal growth retardation J:170999
increased embryonic tissue cell apoptosis J:170999
lethality throughout fetal growth and development, complete penetrance J:170999
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory