65 phenotypes from 9 alleles in 14 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Meox2tm1(cre)Sor/? Nrastm1Zhng/Nrastm1Zhng involves: 129S4/SvJae * C57BL/6	normal neoplasm	J:174880
Nrastm1.1Emfu/Nras+ involves: 129S1/Sv * FVB/N	decreased body weight	J:189834
Nrastm1.1Emfu/Nrastm1.1Emfu involves: 129S1/Sv * FVB/N	abnormal granulocyte differentiation	J:189834
	abnormal leukocyte cell number	J:189834
	abnormal thymus morphology	J:189834
	decreased monocyte cell number	J:189834
	decreased spleen weight	J:189834
	increased granulocyte number	J:189834
	increased T cell number	J:189834
	pale liver	J:189834
	postnatal growth retardation	J:189834
	preweaning lethality, complete penetrance	J:189834
	weight loss	J:189834
Nrastm1b(EUCOMM)Hmgu/Nras+ C57BL/6N-Nrastm1b(EUCOMM)Hmgu/H	increased circulating glucose level	J:211773
	increased circulating HDL cholesterol level	J:211773
	short tibia	J:211773
Nrastm1b(EUCOMM)Hmgu/Nrastm1b(EUCOMM)Hmgu C57BL/6N-Nrastm1b(EUCOMM)Hmgu/H	preweaning lethality, complete penetrance	J:211773
Nrastm1Mok/Nrastm1Mok either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)	no abnormal phenotype detected	J:135610
Nrastm1Mok/Nrastm1Mok involves: 129S/SvEv * C57BL/6 * DBA/2	chylous ascites	J:159024
Nrastm1Rak/Nrastm1Rak involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:23318
Nrastm1Tyj/Nras+ Meox2tm1(cre)Sor/Meox2+ B6.Cg-Nrastm1Tyj Meox2tm1(cre)Sor	abnormal definitive hematopoiesis	J:305401
	abnormal fetal liver hematopoietic progenitor cell morphology	J:305401
	abnormal heart development	J:305401
	abnormal heart morphology	J:305401
	abnormal myocardial trabeculae morphology	J:305401
	abnormal pulmonary valve development	J:305401
	decreased fetal size	J:305401
	double outlet right ventricle	J:305401
	hepatic necrosis	J:305401
	hydrops fetalis	J:305401
	increased erythroid progenitor cell number	J:305401
	increased hematopoietic stem cell number	J:305401
	lethality throughout fetal growth and development, complete penetrance	J:305401
	pallor	J:305401
	pulmonary valve stenosis	J:305401
	small liver	J:305401
	thin myocardium	J:305401
	thin ventricle myocardium compact layer	J:305401
	thin ventricular wall	J:305401
	ventricular septal defect	J:305401
Nrastm1Tyj/Nras+ Meox2tm1(cre)Sor/Meox2+ involves: 129S4/SvJaeSor * C57BL/6	prenatal lethality, complete penetrance	J:174880
Nrastm1Tyj/Nras+ Tg(Fabp1-cre)1Jig/0 involves: C57BL/6 * FVB/N	normal digestive/alimentary phenotype	J:132357
Nrastm1Tyj/Nras+ Tg(Tek-cre)1Ywa/0 B6.Cg-Nrastm1Tyj Tg(Tek-cre)1Ywa	abnormal myocardial trabeculae morphology	J:305401
	double outlet right ventricle	J:305401
	lethality throughout fetal growth and development, complete penetrance	J:305401
	pulmonary valve stenosis	J:305401
	thin ventricle myocardium compact layer	J:305401
	ventricular septal defect	J:305401
Nrastm1Tyj/Nras+ Tg(Tnnt2-cre)5Blh/0 B6.Cg-Nrastm1Tyj Tg(Tnnt2-cre)5Blh	normal cardiovascular system phenotype	J:305401
	normal mortality/aging	J:305401
Nrastm1Tyj/Nras+ Tg(Vil1-cre)20Syr/0 involves: C57BL/6 * DBA/2	decreased physiological sensitivity to xenobiotic	J:132357
Nrastm1Tyj/Nras+ Tg(Tyr-cre)1Lru/0 involves: C57BL/6 * DBA/2	abnormal behavior	J:198244
	abnormal cranium morphology	J:198244
	abnormal gait	J:198244
	hyperpigmentation	J:198244
	hyperresponsive to tactile stimuli	J:198244
	impaired coordination	J:198244
	premature death	J:198244
	tremors	J:198244
Nrastm1Tyj/Nras+ Tg(Tyr-cre/ERT2)1Lru/0 involves: C57BL/6 * DBA/2	abnormal skin morphology	J:198244
	hyperpigmentation	J:198244
Nrastm1Tyj/Nrastm1Tyj Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	abnormal definitive hematopoiesis	J:204263
	abnormal myelopoiesis	J:174880
	anemia	J:204263
	enlarged spleen	J:174880, J:204263
	increased acute lymphoblastic leukemia incidence	J:204263
	increased leukocyte cell number	J:204263
	increased monocyte cell number	J:204263
	increased neutrophil cell number	J:204263
	myeloid hyperplasia	J:204263
	premature death	J:204263
Nrastm1Tyj/Nrastm1Tyj Tg(Tyr-cre)1Lru/0 involves: C57BL/6 * DBA/2	abnormal behavior	J:198244
	abnormal cranium morphology	J:198244
	abnormal gait	J:198244
	abnormal leptomeninges pigmentation	J:198244
	abnormal melanocyte morphology	J:198244
	abnormal melanocyte proliferation	J:198244
	abnormal skin morphology	J:198244
	hyperpigmentation	J:198244
	hyperresponsive to tactile stimuli	J:198244
	impaired coordination	J:198244
	increased melanoma incidence	J:198244
	premature death	J:198244
	tremors	J:198244
Nrastm1Tyj/Nrastm1Tyj Tg(Tyr-cre/ERT2)1Lru/0 involves: C57BL/6 * DBA/2	abnormal skin morphology	J:198244
	hyperpigmentation	J:198244
	normal neoplasm	J:198244
Nrastm1Tyj/Nrastm2.1Tyj Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	normal hematopoietic system phenotype	J:204263
	normal mortality/aging	J:204263
Nrastm3Emfu/Nrastm3Emfu involves: 129S1/Sv * C57BL/6J	no abnormal phenotype detected	J:199340
Nrastm4Emfu/Nrastm4Emfu involves: 129S1/Sv * C57BL/6J	no abnormal phenotype detected	J:199340