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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ncf1
neutrophil cytosolic factor 1
MGI:97283
53 phenotypes from 5 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ncf1em1(IMPC)Mbp/Ncf1em1(IMPC)Mbp
C57BL/6N-Ncf1em1(IMPC)Mbp/MbpMmucd
abnormal behavior J:211773
abnormal eye morphology J:211773
abnormal heart morphology J:211773
abnormal kidney morphology J:211773
abnormal lung morphology J:211773
abnormal lymph node morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
decreased anxiety-related response J:211773
decreased locomotor activity J:211773
decreased thigmotaxis J:211773
enlarged kidney J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased heart atrium size J:211773
single kidney J:211773
small kidney J:211773
Ncf1em1Nansh/Ncf1em1Nansh
involves: C57BL/6J
normal hematopoietic system phenotype J:329553
normal immune system phenotype J:329553
increased susceptibility to induced morbidity/mortality J:329553
Ncf1m1J/Ncf1m1J
B6.Cg-Dock7m +/+ Leprdb/J
abnormal macrophage physiology J:83428
decreased susceptibility to Orthomyxoviridae infection J:145306
impaired granulocyte bactericidal activity J:83428
Ncf1m1J/Ncf1m1J
involves: C57BL/6
oxidative stress J:207291
Ncf1tm1Hbd/Ncf1tm1Hbd
involves: 129
abnormal bile duct morphology J:74593
abnormal lung morphology J:74593
abnormal neutrophil physiology J:74593, J:77597
abnormal vascular endothelial cell physiology J:97513
granulomatous inflammation J:74593
liver abscess J:74593
skin lesions J:74593
Ncf1tm1Hbd/Ncf1tm1Hbd
involves: C57BL/6
normal immune system phenotype J:118561
Ncf1tm1Shl/Ncf1tm1Shl
B6.129S2-Ncf1tm1Shl
abnormal angiogenesis J:142617
abnormal cardiac muscle contractility J:133916
abnormal cardiovascular system physiology J:111142
abnormal heart morphology J:133916
abnormal inflammatory response J:142617
abnormal locomotor activation J:111410
abnormal postnatal growth J:142617
abnormal response to cardiac infarction J:133916
abnormal spatial learning J:111410
abnormal vascular smooth muscle physiology J:111142
abnormal vascular wound healing J:142617
cardiac hypertrophy J:133916
dilated heart left ventricle J:133916
enhanced long-term potentiation J:111410
granulomatous inflammation J:111142
impaired cued conditioning behavior J:111410
increased angiotensin I-converting enzyme activity J:111142
increased circulating renin level J:111142
increased systemic arterial blood pressure J:111142
reduced long-term potentiation J:111410
Ncf1tm1Shl/Ncf1tm1Shl
involves: 129S2/SvPas
abnormal intestinal goblet cell morphology J:206181
Ncf1tm1Shl/Ncf1tm1Shl
involves: 129S2/SvPas * C57BL/6J
abnormal response to infection J:28267
decreased vasoconstriction J:120187
increased acute inflammation J:28267
increased susceptibility to induced morbidity/mortality J:28267
increased susceptibility to infection J:28267

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory