Rab8a Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rab8a
RAB8A, member RAS oncogene family
MGI:96960

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdc42^tm1Brak/Cdc42⁺ Rab8a^tm1.1Aha/Rab8a⁺ Tg(Vil1-cre)997Gum/0 involves: C57BL/6J * SJL	abnormal cellular glucose uptake	J:184563
	abnormal crypts of Lieberkuhn morphology	J:184563
	abnormal intestine physiology	J:184563
	abnormal Paneth cell morphology	J:184563
	intestinal edema	J:184563
Rab8a^tm1.2Aha/Rab8a^tm1.2Aha Rab8b^tm1.2Aha/Rab8b^tm1.2Aha involves: BALB/cJ * C57BL/6 * SJL	abnormal small intestinal microvillus morphology	J:211898
	normal cellular phenotype	J:211898
	postnatal lethality, complete penetrance	J:211898
	normal respiratory system phenotype	J:211898
	normal vision/eye phenotype	J:211898

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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