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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Il2ra
interleukin 2 receptor, alpha chain
MGI:96549
66 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Il2raM1J/Il2raM1J
involves: 129S4/SvJae * C57BL/6 		abnormal regulatory T cell physiology J:268677
Il2ratm1b(EUCOMM)Wtsi/Il2ratm1b(EUCOMM)Wtsi
C57BL/6N-Il2ratm1b(EUCOMM)Wtsi/Orl 		abnormal cholesterol homeostasis J:211773
abnormal colon morphology J:211773
abnormal contextual conditioning behavior J:211773
abnormal duodenum morphology J:211773
abnormal freezing behavior J:211773
abnormal locomotor behavior J:211773
abnormal spleen morphology J:211773
abnormal vertebrae morphology J:211773
decreased blood urea nitrogen level J:211773
decreased body length J:211773
decreased bone mineral density J:211773
decreased circulating alkaline phosphatase level J:211773
decreased circulating calcium level J:211773
decreased circulating cholesterol level J:211773
decreased circulating glucose level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
decreased erythrocyte cell number J:211773
decreased exploration in new environment J:211773
decreased heart weight J:211773
decreased hematocrit J:211773
decreased hemoglobin content J:211773
decreased locomotor activity J:211773
decreased lymphocyte cell number J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular hemoglobin concentration J:211773
decreased mean corpuscular volume J:211773
decreased vertical activity J:211773
enlarged lymph nodes J:211773
improved glucose tolerance J:211773
increased circulating aspartate transaminase level J:211773
increased circulating phosphate level J:211773
increased large unstained cell number J:211773
increased neutrophil cell number J:211773
prolonged PR interval J:211773
Il2ratm1Dw/Il2ratm1Dw
B6.129S4-Il2ratm1Dw 		abnormal induced morbidity/mortality J:125748
abnormal regulatory T cell physiology J:125748
abnormal T cell activation J:125748
anemia J:125748
decreased body size J:125748
lymphoid hyperplasia J:125748
Il2ratm1Dw/Il2ratm1Dw
B6.129S4-Il2ratm1Dw/J 		abnormal salivary gland duct morphology J:125129
abnormal salivary gland morphology J:125129
decreased salivation J:125129
lacrimal gland inflammation J:125129
large intestinal inflammation J:125129
lung inflammation J:125129
salivary gland inflammation J:125129
Il2ratm1Dw/Il2ratm1Dw
involves: 129S4/SvJae * C57BL/6 		abnormal B cell physiology J:64279
abnormal lymph organ size J:64279
abnormal T cell morphology J:64279
abnormal T cell physiology J:64279
cachexia J:64279
colitis J:64279
decreased hematocrit J:64279
diarrhea J:64279
enlarged lymph nodes J:64279
enlarged spleen J:64279
hemolytic anemia J:64279
increased IgA level J:64279
increased IgG1 level J:64279
increased IgG2a level J:64279
increased IgG2b level J:64279
increased IgG level J:64279
increased lymphocyte cell number J:64279
increased memory T cell number J:64279
premature death J:64279
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory