56 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Hoxa1tm1Ipc/Hoxa1tm1Ipc Hoxb1tm1Ipc/Hoxb1tm1Ipc involves: 129S2/SvPas * 129S7/SvEvBrd	abnormal neural crest cell delamination	J:71033
	abnormal neural crest cell migration	J:71033
	normal embryo phenotype	J:71033
	normal muscle phenotype	J:124278
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc Hoxb1tm3Mrc/Hoxb1+ involves: 129S1/Sv * 129X1/SvJ	abnormal neural crest cell migration	J:41540
	abnormal neuron differentiation	J:41540
	abnormal pharyngeal pouch morphology	J:41540
	abnormal rhombomere morphology	J:41540
	absent parathyroid glands	J:41540
	absent second pharyngeal arch	J:41540
	small thymus	J:41540
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc Hoxb1tm3Mrc/Hoxb1tm3Mrc involves: 129S1/Sv * 129X1/SvJ	abnormal digastric posterior belly morphology	J:41540
	abnormal neural crest cell migration	J:41540
	abnormal neuron differentiation	J:41540
	abnormal rhombomere morphology	J:41540
	abnormal stylohyoid muscle morphology	J:41540
	abnormal third pharyngeal pouch morphology	J:41540
	absent facial muscle	J:41540
	absent levator labii superioris muscle	J:41540
	absent orbicularis oculi muscle	J:41540
	absent parathyroid glands	J:41540
	absent rhombomere 4	J:41540
	absent rhombomere 5	J:41540
	absent second pharyngeal arch	J:41540
	absent second pharyngeal pouch	J:41540
	absent stapes	J:41540
	absent zygomaticus muscle	J:41540
	athymia	J:41540
	increased hindbrain apoptosis	J:41540
	pulmonary hypoplasia	J:41540
	small incus	J:41540
	small malleus	J:41540
Hoxa1tm3.1Mrc/Hoxa1tm4(Hoxb1)Mrc Hoxb1tm5Mrc/Hoxb1tm8(Hoxa1)Mrc involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6	abnormal blinking	J:119279
	facial paralysis	J:119279
Hoxa1tm4(Hoxb1)Mrc/Hoxa1tm4(Hoxb1)Mrc Hoxb1tm5Mrc/Hoxb1tm8(Hoxa1)Mrc involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6	abnormal facial nerve morphology	J:119279
	abnormal reflex	J:119279
Hoxa1tm4(Hoxb1)Mrc/Hoxa1tm4(Hoxb1)Mrc Hoxb1tm8(Hoxa1)Mrc/Hoxb1tm8(Hoxa1)Mrc involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6	no abnormal phenotype detected	J:119279
Hoxa1tm5Mrc/Hoxa1+ Hoxb1tm5Mrc/Hoxb1tm5Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal facial nerve morphology	J:119279
	abnormal reflex	J:119279
	paralysis	J:119279
	small facial motor nucleus	J:119279
Hoxa1tm5Mrc/Hoxa1tm5Mrc Hoxb1tm5Mrc/Hoxb1tm5Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal nervous system phenotype	J:119279
Hoxb1tm1(cre)Og/Hoxb1+ Pbx3tm1Og/Pbx3tm1Og involves: 129S/SvEv * 129S4/SvJae * C57BL/6	abnormal behavior	J:130927
	abnormal limb posture	J:130927
	abnormal locomotor coordination	J:130927
	abnormal neuron differentiation	J:130927
	abnormal neuron morphology	J:130927
	abnormal spinal cord dorsal horn morphology	J:130927
	bradykinesia	J:130927
	decreased body size	J:130927
	decreased neuron number	J:130927
	decreased thermal nociceptive threshold	J:130927
	hyporesponsive to tactile stimuli	J:130927
	impaired coordination	J:130927
	improved righting response	J:130927
	increased startle reflex	J:130927
	limb grasping	J:130927
Hoxb1tm1.1Mist/Hoxb1tm1.1Mist Tg(Hoxb1-cre)r4Mist/0 Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * CD-1	abnormal brainstem morphology	J:197162
	abnormal cochlear outer hair cell morphology	J:197162
	abnormal cochlear VIII nucleus morphology	J:197162
	abnormal organ of Corti morphology	J:197162
	abnormal pons morphology	J:197162
	abnormal susceptibility to hearing loss	J:197162
	increased or absent threshold for auditory brainstem response	J:197162
	increased susceptibility to age-related hearing loss	J:197162
Hoxb1tm1Mist/Hoxb1tm1Mist Tg(Hoxb1-cre)r4Mist/0 Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * CD-1	abnormal brainstem morphology	J:197162
	abnormal cochlear outer hair cell morphology	J:197162
	abnormal cochlear VIII nucleus morphology	J:197162
	abnormal organ of Corti morphology	J:197162
	abnormal pons morphology	J:197162
	increased or absent threshold for auditory brainstem response	J:197162
	increased susceptibility to age-related hearing loss	J:197162