Grik5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Grik5
glutamate receptor, ionotropic, kainate 5 (gamma 2)
MGI:95818

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Grik5^em1(IMPC)Mbp/Grik5^em1(IMPC)Mbp C57BL/6N-Grik5^em1(IMPC)Mbp/MbpMmucd	abnormal brain morphology	J:211773
	abnormal eye morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal vitreous body morphology	J:211773
	anophthalmia	J:211773
	cataract	J:211773
	decreased body length	J:211773
	decreased brain size	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	small liver	J:211773
Grik5^tm1Cont/Grik5^tm1Cont 129S/SvEv-Grik5^tm1Cont	abnormal CNS synaptic transmission	J:81742
	abnormal excitatory postsynaptic currents	J:81742
	short excitatory postsynaptic current decay time	J:81742
Grik5^tm1Dgen/Grik5^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	increased startle reflex	J:101679
	increased susceptibility to pharmacologically induced seizures	J:101679
	increased thermal nociceptive threshold	J:101679

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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