Grik2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Grik2
glutamate receptor, ionotropic, kainate 2 (beta 2)
MGI:95815

13 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Grik2^tm1Bvis/Grik2^tm1Bvis 129S/Sv-Grik2^tm1Bvis	abnormal CNS synaptic transmission	J:107698
	abnormal excitatory postsynaptic potential	J:107698
	abnormal long-term potentiation	J:107698
	abnormal single cell response	J:107698
	increased susceptibility to pharmacologically induced seizures	J:107698
Grik2^tm1Sfh/Grik2^tm1Sfh involves: 129S1/Sv	abnormal CNS synaptic transmission	J:148310
Grik2^tm1Sfh/Grik2^tm1Sfh involves: 129S1/Sv	decreased paired-pulse facilitation	J:148310
Grik2^tm1Sfh/Grik2^tm1Sfh involves: 129S1/Sv * C57BL/6	abnormal contextual conditioning behavior	J:98109
	abnormal cued conditioning behavior	J:98109
	abnormal glutamate-mediated receptor currents	J:46932
	abnormal long-term potentiation	J:91763
	decreased body weight	J:46932
	decreased fear-related response	J:98109
	decreased paired-pulse facilitation	J:91763
	decreased susceptibility to pharmacologically induced seizures	J:46932
	reduced long-term potentiation	J:98109

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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