75 phenotypes from 5 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
En1tm2(cre)Wrst/En1+ Gbx2tm1.1Mrt/Gbx2tm1.1Alj involves: 129/Sv * C57BL/6 * SJL * Swiss Webster	abnormal cerebellar foliation	J:79431
	abnormal cerebellum development	J:79431
	abnormal midbrain development	J:79431
	abnormal midbrain-hindbrain boundary morphology	J:79431
	abnormal postnatal growth	J:79431
	cerebellum vermis hypoplasia	J:79431
	decreased body weight	J:79431
	decreased embryonic neuroepithelial cell proliferation	J:79431
	decreased embryonic neuroepithelium thickness	J:79431
	increased inferior colliculus size	J:79431
	normal mortality/aging	J:79431
	normal nervous system phenotype	J:79431
	postnatal lethality, incomplete penetrance	J:79431
Gbx2tm1.1(cre/ERT2)Jyhl/Gbx2tm1.1Mrt involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	absent cerebellum	J:147282
Gbx2tm1.1Alj/Gbx2tm1.1Alj involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:79431
Gbx2tm1.1Mrt/Gbx2tm1.1Alj involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * SJL	no abnormal phenotype detected	J:79431
Gbx2tm1.1Mrt/Gbx2tm1.1Mrt B6.129-Gbx2tm1.1Mrt	abnormal aortic arch morphology	J:100584
	abnormal cardiovascular system morphology	J:100584
	abnormal cerebellum morphology	J:100584
	abnormal fourth pharyngeal arch artery morphology	J:100584
	abnormal innervation	J:100584
	abnormal neural crest cell migration	J:100584
	abnormal neural crest cell morphology	J:100584
	abnormal styloid process morphology	J:100584
	abnormal trigeminal ganglion morphology	J:100584
	abnormal vascular endothelial cell differentiation	J:100584
	absent trigeminal nerve	J:100584
	cleft palate	J:100584
	cyanosis	J:100584
	decreased neural crest cell number	J:100584
	double outlet right ventricle	J:100584
	fusion of glossopharyngeal and vagus nerve	J:100584
	fusion of middle ear ossicles	J:100584
	interrupted aortic arch, type b	J:100584
	middle ear ossicle hypoplasia	J:100584
	neonatal lethality, complete penetrance	J:100584
	otic capsule hypoplasia	J:100584
	overriding aortic valve	J:100584
	perimembraneous ventricular septal defect	J:100584
	retroesophageal right subclavian artery	J:100584
	right aortic arch	J:100584
	styloid process hypoplasia	J:100584
Gbx2tm1.1Mrt/Gbx2tm1.1Mrt either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J) or (involves: 129S1/Sv * 129X1/SvJ * FVB/N)	abnormal cerebellum development	J:42110
	abnormal choroid plexus morphology	J:42110
	abnormal forebrain development	J:42110
	abnormal hindbrain morphology	J:42110
	abnormal inferior colliculus morphology	J:42110
	abnormal locus ceruleus morphology	J:42110
	abnormal membranous labyrinth morphology	J:42110
	abnormal metencephalon morphology	J:42110
	abnormal midbrain development	J:42110
	abnormal midbrain morphology	J:42110
	abnormal midbrain-hindbrain boundary development	J:42110
	abnormal midbrain-hindbrain boundary morphology	J:42110
	abnormal motor neuron morphology	J:42110
	abnormal pons morphology	J:42110
	absent cerebellum	J:42110
	absent supraoccipital bone	J:42110
	neonatal lethality, complete penetrance	J:42110
	small otic vesicle	J:42110
Gbx2tm1.1Mrt/Gbx2tm1.1Mrt involves: 129S1/Sv * 129X1/SvJ * Swiss Webster	abnormal cochlear ganglion morphology	J:98487
	abnormal cochlear sensory epithelium morphology	J:98487
	abnormal crista ampullaris morphology	J:98487
	abnormal hindbrain development	J:98487
	abnormal inner ear morphology	J:98487
	abnormal membranous labyrinth morphology	J:98487
	abnormal metencephalon morphology	J:98487
	abnormal organ of Corti morphology	J:98487
	abnormal rhombomere 5 morphology	J:98487
	abnormal vestibular saccular macula morphology	J:98487
	absent cochlear ganglion	J:98487
	absent common crus	J:98487
	absent endolymphatic duct	J:98487
	absent lateral semicircular canal	J:98487
	absent posterior semicircular canal	J:98487
	absent scala media	J:98487
	absent superior semicircular canal	J:98487
	absent vestibular saccule	J:98487
	decreased cochlea coiling	J:98487
	inner ear cyst	J:98487
	small otic vesicle	J:98487
Gbx2tm1.1Mrt/Gbx2tm1.2Alj involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ	abnormal cardiovascular system morphology	J:79431
	abnormal nervous system morphology	J:79431
	abnormal skeleton morphology	J:79431
	preweaning lethality, complete penetrance	J:79431
Gbx2tm1Mrt/Gbx2+ Tg(Nes-cre)1Atp/? involves: 129S1/Sv * 129X1/SvJ * FVB/N	no abnormal phenotype detected	J:111945