Fmr1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fmr1
fragile X messenger ribonucleoprotein 1
MGI:95564

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cyfip2^{tm1(KOMP)Vlcg}/Cyfip2⁺ Fmr1^tm1Cgr/Y involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NTac	abnormal anxiety-related response	J:219363
	abnormal dendritic spine morphology	J:219363
	decreased startle reflex	J:219363
	hyperactivity	J:219363
	increased prepulse inhibition	J:219363
	increased stereotypic behavior	J:219363
Fmr1^tm1Cgr/Fmr1^tm1Cgr Rgs4^tm1Dgen/Rgs4^tm1Dgen B6.129P2-Rgs4^tm1Dgen Fmr1^tm1Cgr	abnormal object recognition memory	J:171292
	normal behavior/neurological phenotype	J:171292
	normal growth/size/body region phenotype	J:171292
	hyperactivity	J:171292
	increased testis weight	J:171292
	increased vertical activity	J:171292
Fmr1^tm1Cgr/Y Grm5^tm1Rod/Grm5⁺ involves: 129P2/OlaHsd * C57BL/6 * FVB	audiogenic seizures	J:127792
	normal behavior/neurological phenotype	J:127792
	normal growth/size/body region phenotype	J:127792
	increased testis weight	J:127792
	normal nervous system phenotype	J:127792
Fmr1^tm1Cgr/Y Tg(ACTB-Eif4e)#Ppp/0 involves: 129P2/OlaHsd * C57BL/6	abnormal brain morphology	J:227667
	abnormal contextual conditioning behavior	J:227667
	abnormal response to novel object	J:227667
	abnormal social investigation	J:227667
	abnormal spatial learning	J:227667
	hyperactivity	J:227667
	increased anxiety-related response	J:227667
	increased stereotypic behavior	J:227667

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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