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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Flg
filaggrin
MGI:95553
49 phenotypes from 2 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Flgft/Flgft
B6.Cg-Flgft
abnormal epidermal layer morphology J:202453
abnormal hair cuticle J:202453
acanthosis J:151110, J:202453
dry skin J:202453
normal immune system phenotype J:151110, J:202453
impaired skin barrier function J:151110
increased IgE level J:151110, J:202453
increased IgG1 level J:151110
increased IgG2a level J:151110
increased IgG level J:151110
increased interferon-gamma secretion J:151110
increased interleukin-4 secretion J:151110
increased interleukin-5 secretion J:151110
increased interleukin-10 secretion J:151110
increased interleukin-13 secretion J:151110
increased interleukin-17 secretion J:151110
increased splenocyte proliferation J:151110
orthokeratosis J:202453
scaly skin J:202453
Flgft/Flgft
involves: C57BL/6
acanthosis J:151110
normal integument phenotype J:151110
orthokeratosis J:151110
skin inflammation J:151110
Flgft/Flgft
involves: C57BL/6J
abnormal epidermis stratum granulosum morphology J:5286
abnormal skin appearance J:5286
abnormal tail ring morphology J:5286
acanthosis J:66567
decreased body size J:5286
flaky skin J:5286
hyperkeratosis J:66567
postnatal lethality J:5286
short ears J:5286
small ears J:5286
tail necrosis J:5286
thick ears J:5286
Flgft/Flgft
involves: C57BL/6JJcl
normal integument phenotype J:202316
Flgft/Flgft
Not Specified
dermatitis J:198332
impaired skin barrier function J:192725, J:198332
Flgft/Flgft
STOCK a/a Tmem79ma Flgft/J
abnormal cytokine level J:204304
abnormal skin morphology J:204304
abnormal skin physiology J:204304
acanthosis J:204304
dermatitis J:204304
epidermal spongiosis J:204304
flaky skin J:204304
hyperkeratosis J:204304
scaly skin J:204304
thick epidermis J:204304
thin epidermis stratum granulosum J:204304
Flgtm1Amag/Flgtm1Amag
involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac
abnormal epidermis stratum corneum morphology J:198332
abnormal humoral immune response J:198332
abnormal lipid level J:198332
abnormal skin morphology J:198332
decreased keratohyalin granule number J:198332
dermatitis J:198332
dry skin J:198332
epidermal desquamation J:198332
hyperkeratosis J:198332
increased cholesterol level J:198332
increased IgE level J:198332
increased IgG1 level J:198332
increased inflammatory response J:229771
increased susceptibility to type IV hypersensitivity reaction J:198332
normal integument phenotype J:198332
scaly skin J:198332
shiny skin J:198332
skin lesions J:198332

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory