Fgr Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgr
FGR proto-oncogene, Src family tyrosine kinase
MGI:95527

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fgr^tm1Hev/Fgr^tm1Hev Hck^tm1Hev/Hck^tm1Hev involves: 129S7/SvEvBrd * C57BL/6J	abnormal macrophage morphology	J:59037
	abnormal macrophage physiology	J:59037
	decreased angiogenesis	J:89137
	impaired macrophage phagocytosis	J:16994
	increased susceptibility to bacterial infection	J:16994
Fgr^tm1Hev/Fgr^tm1Hev Hck^tm1Hev/Hck^tm1Hev Lyn^tm1Sor/Lyn^tm1Sor B6.Cg-Hck^tm1Hev Fgr^tm1Hev Lyn^tm1Sor	abnormal inflammatory response	J:113463
	abnormal neutrophil physiology	J:113463

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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