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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fgfr4
fibroblast growth factor receptor 4
MGI:95525
14 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fgfr3tm1Led/Fgfr3tm1Led
Fgfr4tm1Cxd/Fgfr4tm1Cxd
involves: 129S6/SvEvTac * Black Swiss 		abnormal pulmonary elastic fiber morphology J:50677
absent pulmonary alveoli J:50677
decreased body size J:50677
dehydration J:50677
emphysema J:50677
impaired lung alveolus development J:50677
infertility J:50677
postnatal growth retardation J:50677
premature death J:50677
Fgfr4tm1Axul/Fgfr4+
Tg(WapTgfa)215Bri/0
B6.Cg-Fgfr4tm1Axul Tg(WapTgfa)215Bri 		increased mammary adenocarcinoma incidence J:156750
increased metastatic potential J:156750
Fgfr4tm1Axul/Fgfr4tm1Axul
Tg(MMTV-PyVT)634Mul/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal tumor susceptibility J:156750
Fgfr4tm1Axul/Fgfr4tm1Axul
Tg(WapTgfa)215Bri/0
B6.Cg-Fgfr4tm1Axul Tg(WapTgfa)215Bri 		increased mammary adenocarcinoma incidence J:156750
increased metastatic potential J:156750
Fgfr4tm1Axul/Fgfr4tm1Axul
Tg(WapTgfa)215Bri/0
FVB.Cg-Fgfr4tm1Axul Tg(WapTgfa)215Bri 		increased mammary adenocarcinoma incidence J:156750
Fgfr4tm1Cxd/Fgfr4tm1Cxd
Tg(Myl2-FGF19)1Dfre/0
involves: 129S6/SvEvTac * FVB/N 		decreased incidence of tumors by chemical induction J:187236
decreased liver tumor incidence J:187236
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory