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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Erg
ETS transcription factor
MGI:95415
38 phenotypes from 7 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ergem1(IMPC)Bay/Erg+
C57BL/6N-Ergem1(IMPC)Bay/Bay 		abnormal coat appearance J:211773
abnormal eye posterior chamber depth J:211773
abnormal spleen morphology J:211773
decreased leukocyte cell number J:211773
increased heart left ventricle size J:211773
thick ventricular wall J:211773
Ergem1(IMPC)Bay/Ergem1(IMPC)Bay
C57BL/6N-Ergem1(IMPC)Bay/Bay 		prenatal lethality prior to heart atrial septation J:211773
preweaning lethality, complete penetrance J:211773
Ergmld2/Erg+
involves: 129S1/Sv * C57BL/6 		decreased hematopoietic stem cell number J:137835
decreased transitional stage B cell number J:137835
normal hematopoietic system phenotype J:137835
thrombocytopenia J:137835
Ergmld2/Ergmld2
involves: 129S1/Sv * C57BL/6 		abnormal embryonic erythropoiesis J:137835
embryonic growth retardation J:137835
embryonic lethality during organogenesis, complete penetrance J:137835
Ergtm1.1Iwamo/Ergtm1.1Iwamo
Tg(Gdf5-cre,-ALPP)1Kng/?
involves: 129S4/SvJaeSor * C57BL/6 * FVB/N 		abnormal articular cartilage morphology J:243715
increased susceptibility to induced arthritis J:243715
osteoarthritis J:243715
Ergtm1.1Path/Ergtm1.1Path
Not Specified 		abnormal vein morphology J:227456
abnormal venule morphology J:227456
heart right ventricle hypertrophy J:227456
increased right ventricle systolic pressure J:227456
increased vascular endothelial cell proliferation J:227456
lethality, complete penetrance J:227456
lung hemorrhage J:227456
pancytopenia J:227456
pulmonary edema J:227456
pulmonary hypertension J:227456
venoocclusion J:227456
Ergtm1.2Iwamo/Ergtm1.2Iwamo
involves: 129S4/SvJaeSor * C57BL/6 * FVB/N 		embryonic lethality during organogenesis, complete penetrance J:243715
Ergtm1Poet/Ergtm1Poet
involves: 129S6/SvEvTac * C57BL/6 		no abnormal phenotype detected J:188920
Ergtm2Poet/Ergtm2Poet
involves: 129S6/SvEvTac * C57BL/6 		abnormal developmental vascular remodeling J:188920
abnormal heart development J:188920
abnormal placental labyrinth vasculature morphology J:188920
abnormal vascular development J:188920
decreased embryo size J:188920
embryonic lethality during organogenesis, complete penetrance J:188920
internal hemorrhage J:188920
intracranial hemorrhage J:188920
pericardial effusion J:188920
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory