Selenop Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Selenop
selenoprotein P
MGI:894288

36 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Selenop^tm1Kohr/Selenop^tm1Kohr involves: 129P2/OlaHsd * C57BL/6	abnormal gait	J:82244
	ataxia	J:82244
	decreased body length	J:82244
	decreased body weight	J:82244
	impaired coordination	J:82244
	premature death	J:82244
	short tail	J:82244
Selenop^tm1Rfb/Selenop^tm1Rfb B6.129-Selenop^tm1Rfb	abnormal motor capabilities/coordination/movement	J:191114
	abnormal selenium level	J:121127
	abnormal spatial learning	J:191114
	decreased grip strength	J:191114
	decreased grooming behavior	J:191114
	decreased liver function	J:134536
	decreased locomotor activity	J:191114
	decreased vertical activity	J:191114
	impaired coordination	J:191114
	increased hepatocyte apoptosis	J:134536
	increased susceptibility to induced morbidity/mortality	J:121127
	increased susceptibility to parasitic infection	J:134536
	short stride length	J:121127
Selenop^tm1Rfb/Selenop^tm1Rfb involves: 129 * C57BL/6J	abnormal parental behavior	J:82921
	abnormal selenium level	J:82921
	impaired coordination	J:82921
	increased susceptibility to weight loss	J:82921
	postnatal lethality, incomplete penetrance	J:82921
	premature death	J:82921
	reduced male fertility	J:82921
Selenop^tm2Rfb/Selenop^tm2Rfb B6.Cg-Selenop^tm2Rfb	abnormal selenium level	J:121127
	abnormal sperm flagellum morphology	J:121127
	abnormal sperm midpiece morphology	J:121127
	abnormal sperm mitochondrial sheath morphology	J:121127
	decreased litter size	J:121127
	decreased survivor rate	J:121127
	hairpin sperm flagellum	J:121127
	hyperactivity	J:121127
	impaired righting response	J:121127
	increased susceptibility to induced morbidity/mortality	J:121127
	reduced male fertility	J:121127
	tremors	J:121127
Selenop^tm3.1Rfb/Selenop^tm3.1Rfb Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * DBA	abnormal gait	J:192636
	abnormal selenium level	J:192636
	decreased body weight	J:192636
	increased urine selenium level	J:192636
	limb grasping	J:192636
	oligozoospermia	J:192636
	teratozoospermia	J:192636

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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