Chrm1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chrm1
cholinergic receptor, muscarinic 1, CNS
MGI:88396

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Chrm1^tm1Jwe/Chrm1^tm1Jwe Chrm3^tm1Jwe/Chrm3^tm1Jwe involves: 129S6/SvEvTac * CF-1	normal nervous system phenotype	J:112505
Chrm1^tm1Jwe/Chrm1^tm1Jwe Chrm4^tm1Jwe/Chrm4^tm1Jwe involves: 129S6/SvEvTac * CF-1	abnormal CNS synaptic transmission	J:112505
	decreased synaptic depression	J:112505
Chrm1^tm1Kano/Chrm1^tm1Kano Chrm3^tm1Mmt/Chrm3^tm1Mmt involves: 129X1/SvJ * C57BL/6	abnormal inhibitory postsynaptic currents	J:98902
	abnormal submandibular gland physiology	J:105126
	decreased salivation	J:105126
Chrm1^tm1Kano/Chrm1^tm1Kano Chrm5^tm1Minm/Chrm5^tm1Minm involves: 129X1/SvJ * C57BL/6	decreased digestive secretion	J:104782
	normal endocrine/exocrine gland phenotype	J:105126

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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