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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cd22
CD22 antigen
MGI:88322
7 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Cd22tm1Eac/\Cd22+
\Ptpn6me-v/\Ptpn6+
\Tg(IghelMD4)4Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell negative selection J:110531
abnormal mature B cell morphology J:110531
\Cd22tm1Eac/\Cd22+
\Lyntm1Ard/\Lyn+
\Ptpn6me-v/\Ptpn6+
\Tg(IghelMD4)4Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell negative selection J:110531
abnormal mature B cell morphology J:110531
increased IgM level J:110531
\Cd22tm1Eac/\Cd22+
\Lyntm1Ard/\Lyn+
\Tg(IghelMD4)4Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell negative selection J:110531
abnormal mature B cell morphology J:110531
\Cd22tm1Eac/\Cd22+
\Tg(IghelMD4)4Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal mature B cell morphology J:110531
\Cd22tm1Lam/\Cd22tm1Lam
\Ightm1.2Rsky/\Igh+
involves: 129 * BALB/c * C57BL/6 		abnormal class switch recombination J:125719
\Cd22tm1Lam/\Cd22tm1Lam
\Ightm1.2Rsky/\Ightm1.2Rsky
involves: 129 * BALB/c * C57BL/6 		abnormal B cell activation J:125719
decreased B-1a cell number J:125719
\Cd22tm2Tft/\Cd22tm2Tft
\Endoutm1Tft/\Endoutm1Tft
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 		normal immune system phenotype J:208364
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory