Cacna2d1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cacna2d1
calcium channel, voltage-dependent, alpha2/delta subunit 1
MGI:88295

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cacna2d1^em1(IMPC)Mbp/Cacna2d1^em1(IMPC)Mbp C57BL/6N-Cacna2d1^em1(IMPC)Mbp/MbpMmucd	abnormal freezing behavior	J:211773
	abnormal spleen morphology	J:211773
	decreased bone mineral content	J:211773
	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	decreased prepulse inhibition	J:211773
	decreased startle reflex	J:211773
	enhanced contextual conditioning behavior	J:211773
	impaired glucose tolerance	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased fasting circulating glucose level	J:211773
	increased freezing behavior	J:211773
	increased monocyte cell number	J:211773
	small spleen	J:211773
Cacna2d1^tm1Aschw/Cacna2d1^tm1Aschw involves: Black Swiss	abnormal muscle electrophysiology	J:151101
	decreased cardiac muscle contractility	J:151101
	decreased channel response intensity	J:151101
	distended urinary bladder	J:151101
	increased channel response threshold	J:151101
Cacna2d1^tm1Cptl/Cacna2d1^tm1Cptl involves: 129S7/SvEvBrd * C57BL/6	abnormal CNS synaptic transmission	J:117098
	impaired behavioral response to xenobiotic	J:117098

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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