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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Asl
argininosuccinate lyase
MGI:88084
35 phenotypes from 3 alleles in 1 genetic background
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Allelic Composition
Genetic Background
Annotated Term Reference
Asltm1.1Brle/Asltm1.1Brle
involves: 129S7/SvEvBrd
no abnormal phenotype detected J:180208
Asltm1Brle/Asltm1Brle
involves: 129S7/SvEvBrd
abnormal coat/ hair morphology J:180208
abnormal dermal layer morphology J:180208
abnormal erythrocyte morphology J:180208
abnormal hair follicle morphology J:180208
abnormal myocardial fiber morphology J:180208
abnormal nitric oxide homeostasis J:180208
abnormal renal glomerulus morphology J:180208
acanthocytosis J:180208
decreased body weight J:180208
decreased circulating alanine transaminase level J:180208
decreased circulating arginine level J:180208
decreased circulating aspartate transaminase level J:180208
decreased creatinine clearance J:180208
decreased lymphocyte cell number J:180208
decreased spleen germinal center number J:180208
decreased vasodilation J:180208
epidermal atrophy J:180208
increased circulating ammonia level J:180208
increased circulating citrulline level J:180208
increased macrophage cell number J:180208
increased spleen red pulp amount J:180208
increased systemic arterial diastolic blood pressure J:180208
increased systemic arterial systolic blood pressure J:180208
postnatal growth retardation J:180208
premature death J:180208
small hair follicles J:180208
thymus cortex hypoplasia J:180208
Asltm1Wjc/Asltm1Wjc
involves: 129S7/SvEvBrd
abnormal circulating amino acid level J:101658
abnormal enzyme/coenzyme activity J:101658
abnormal food intake J:101658
decreased circulating arginine level J:101658
normal homeostasis/metabolism phenotype J:101658
increased circulating ammonia level J:101658
increased circulating citrulline level J:101658
increased circulating glutamine level J:101658
lethargy J:101658
postnatal lethality, complete penetrance J:101658

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory