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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Acvr2b
activin receptor IIB
MGI:87912
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Acvr2atm1Hsch/Acvr2a+
Acvr2btm1Enl/Acvr2btm1Enl
involves: 129S1/Sv * 129S4/SvJae * C57BL/6J 		perinatal lethality, complete penetrance J:57262
Acvr2atm1Hsch/Acvr2a+
Acvr2btm1Spo/Acvr2btm1Spo
involves: 129S1/Sv * 129S4/SvJae 		abnormal left-right axis patterning J:114533
lumbar vertebral transformation J:114533
right pulmonary isomerism J:114533
transposition of great arteries J:114533
Acvr2atm1Hsch/Acvr2a+
Acvr2btm1.1Spo/Acvr2btm1.1Spo
involves: 129S1/Sv * 129S4/SvJae * FVB/N 		abnormal left-right axis patterning J:114533
lumbar vertebral transformation J:114533
right pulmonary isomerism J:114533
transposition of great arteries J:114533
Acvr2atm1Hsch/Acvr2atm1Hsch
Acvr2btm1.1Spo/Acvr2btm1.1Spo
involves: 129S1/Sv * 129S4/SvJae * FVB/N 		abnormal embryonic tissue morphology J:114533
embryonic growth arrest J:114533
embryonic lethality between somite formation and embryo turning J:114533
embryonic-extraembryonic boundary constriction J:114533
Acvr2atm1Hsch/Acvr2atm1Hsch
Acvr2btm1Enl/Acvr2b+
involves: 129S1/Sv * 129S4/SvJae * C57BL/6J 		abnormal gastrulation J:57262
abnormal mesoderm development J:57262
abnormal primitive streak elongation J:57262
abnormal rostral-caudal axis patterning J:57262
absent allantois J:57262
absent amnion J:57262
absent head fold J:57262
absent heart tube J:57262
embryonic growth arrest J:57262
embryonic lethality between implantation and somite formation, complete penetrance J:57262
embryonic-extraembryonic boundary constriction J:57262
Acvr2atm1Hsch/Acvr2atm1Hsch
Acvr2btm1Enl/Acvr2btm1Enl
involves: 129S1/Sv * 129S4/SvJae * C57BL/6J 		absent mesoderm J:57262
embryonic growth arrest J:57262
embryonic lethality between implantation and somite formation, complete penetrance J:57262
embryonic-extraembryonic boundary constriction J:57262
failure to gastrulate J:57262
increased embryonic epiblast cell apoptosis J:57262
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory