Dnmt3c Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnmt3c
DNA methyltransferase 3C
MGI:3649996

8 phenotypes from 5 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnmt3c^em1Sky/Dnmt3c^rahu involves: C57BL/6J * CBA * FVB/NJ	decreased testis weight	J:244795
Dnmt3c^em1Sky/Dnmt3c^rahu involves: C57BL/6J * CBA * FVB/NJ	normal reproductive system phenotype	J:244795
Dnmt3c^em2Sky/Dnmt3c^em2Sky involves: C57BL/6 * CBA	decreased testis weight	J:244795
Dnmt3c^em2Sky/Dnmt3c^em2Sky involves: C57BL/6 * CBA	normal reproductive system phenotype	J:244795
Dnmt3c^em2Sky/Dnmt3c^em3Sky involves: C57BL/6 * CBA	azoospermia	J:244795
Dnmt3c^em2Sky/Dnmt3c^em3Sky involves: C57BL/6 * CBA	decreased testis weight	J:244795
Dnmt3c^em4Sky/Dnmt3c^rahu involves: C57BL/6J * CBA * FVB/NJ	azoospermia	J:244795
Dnmt3c^em4Sky/Dnmt3c^rahu involves: C57BL/6J * CBA * FVB/NJ	decreased testis weight	J:244795
Dnmt3c^rahu/Dnmt3c^rahu involves: C57BL/6J * FVB/NJ	abnormal DNA methylation during gametogenesis	J:244795
	abnormal spermatocyte morphology	J:244795
	arrest of male meiosis	J:244795
	azoospermia	J:244795
	decreased testis weight	J:244795
	increased male germ cell apoptosis	J:244795
	male infertility	J:244795
	normal reproductive system phenotype	J:244795
	small testis	J:244795

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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