Dnmt3c^rahu
Chemically induced Allele Detail

Summary

• Symbol: Dnmt3c^rahu
• Name: DNA methyltransferase 3C; rahu
• MGI ID: MGI:6156101
• Gene: Dnmt3c Location: Chr2:153548404-153571933 bp, + strand Genetic Position: Chr2, Syntenic
• Alliance: Dnmt3c^rahu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU-mutagenesis produced an A to G point mutation in exon 18 to create a novel Hpy188I restriction site. (J:244795)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnmt3c Mutation: 13 strains or lines available

References

• Original: J:244795 Jain D, et al., rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline. PLoS Genet. 2017 Aug;13(8):e1006964
• All: 1 reference(s)