27 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Iqsec2em1Alev/Iqsec2em1Alev C57BL/6J-Iqsec2em1Alev	abnormal CNS synaptic transmission	J:280198
	abnormal response to novelty	J:280198
	abnormal response to social novelty	J:280198
	normal behavior/neurological phenotype	J:280198
	impaired spatial learning	J:280198
	increased locomotor activity	J:280198
Iqsec2em1Csbg/Iqsec2+ C57BL/6NHsd-Iqsec2em1Csbg	abnormal CNS synapse formation	J:284750
	abnormal corpus callosum size	J:284750
	abnormal sexual interaction	J:284750
	abnormal spatial working memory	J:284750
	decreased grip strength	J:284750
	impaired spatial learning	J:284750
	increased dentate gyrus size	J:284750
	increased exploration in new environment	J:284750
	increased hippocampus volume	J:284750
	increased locomotor activity	J:284750
	social withdrawal	J:284750
	sporadic seizures	J:284750
Iqsec2em1Csbg/Y C57BL/6NHsd-Iqsec2em1Csbg	sporadic seizures	J:284750
Iqsec2em1Frk/Y involves: C3HeB/FeJ * C57BL/6NJ	abnormal brain interneuron morphology	J:284762
	abnormal GABAergic neuron physiology	J:284762
	abnormal miniature excitatory postsynaptic currents	J:284762
	abnormal sexual interaction	J:284762
	astrocytosis	J:284762
	convulsive seizures	J:284762
	decreased susceptibility to induction of seizure by inducing agent	J:284762
	decreased susceptibility to pharmacologically induced seizures	J:284762
	decreased vocalization	J:284762
	increased anxiety-related response	J:284762
	increased locomotor activity	J:284762
	postnatal growth retardation	J:284762
	premature death	J:284762
Iqsec2em1Frk/Iqsec2+ involves: C3HeB/FeJ * C57BL/6NJ	decreased susceptibility to induction of seizure by inducing agent	J:284762