Hpse2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hpse2
heparanase 2
MGI:2685814

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hpse2^em1(IMPC)J/Hpse2⁺ C57BL/6NJ-Hpse2^em1(IMPC)J/J	cataract	J:211773
	hyperactivity	J:211773
	impaired pupillary reflex	J:211773
Hpse2^em1(IMPC)J/Hpse2^em1(IMPC)J C57BL/6NJ-Hpse2^em1(IMPC)J/J	preweaning lethality, incomplete penetrance	J:211773
Hpse2^{Gt(OST411605)Lex}/Hpse2^{Gt(OST411605)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal intestine morphology	J:219597
	abnormal urinary bladder physiology	J:219597
	abnormal urination pattern	J:219597
	albuminuria	J:219597
	decreased body size	J:219597
	decreased circulating glucose level	J:219597
	decreased circulating serum albumin level	J:219597
	distended urinary bladder	J:219597
	increased circulating alkaline phosphatase level	J:219597
	increased urination frequency	J:219597
	increased urine protein level	J:219597
	lethality at weaning, incomplete penetrance	J:219597
	premature death	J:219597
	normal renal/urinary system phenotype	J:219597
	slow postnatal weight gain	J:219597
	small kidney	J:219597
	urinary bladder fibrosis	J:219597
	urinary incontinence	J:219597
	weight loss	J:219597

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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