Mir155 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mir155
microRNA 155
MGI:2676840

38 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mir155^tm1.1Brd/Mir155^tm1.1Brd B6.129S7-Mir155^tm1.1Brd	decreased regulatory T cell number	J:146268
Mir155^tm1.1Brd/Mir155^tm1.1Brd B6.Cg-Mir155^tm1.1Brd Tyr^c-Brd	abnormal CD4-positive, alpha beta T cell morphology	J:121095
	abnormal CD4-positive, alpha-beta T cell physiology	J:121095
	abnormal dendritic cell physiology	J:121095
	abnormal T-helper 1 cell morphology	J:121095
	decreased IgG1 level	J:121095
	normal immune system phenotype	J:121095
	increased susceptibility to bacterial infection	J:121095
	increased T-helper 2 cell number	J:121095
Mir155^tm1.1Ggard/Mir155^tm1.1Ggard involves: C57BL/6	no abnormal phenotype detected	J:218084
Mir155^tm1.1Rsky/Mir155^tm1.1Rsky B6.Cg-Mir155^tm1Rsky/J	abnormal T cell physiology	J:226678
	abnormal T-helper 17 cell differentiation	J:226678
	decreased effector memory T-helper cell number	J:226678
	decreased interleukin-6 secretion	J:226678
	decreased regulatory T cell number	J:226678
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:226678
	decreased T-helper 17 cell number	J:226678
Mir155^tm1.1Rsky/Mir155^tm1.1Rsky involves: 129 * C57BL/6	abnormal B cell physiology	J:121084
	abnormal cytokine secretion	J:121084
	abnormal germinal center B cell physiology	J:121084
	abnormal humoral immune response	J:121084
	abnormal T cell physiology	J:121084
	decreased germinal center B cell number	J:121084
Mir155^tm1Brd/Mir155^tm1Brd involves: 129S7/SvEvBrd * C57BL/6	abnormal B cell physiology	J:121095
	abnormal bronchiole morphology	J:121095
	abnormal class switch recombination	J:121095
	abnormal cytokine secretion	J:121095
	abnormal lung morphology	J:121095
	decreased IgM level	J:121095
	normal immune system phenotype	J:121095
	intestinal inflammation	J:121095
	lung inflammation	J:121095
Mir155^tm1Rsky/Mir155^tm1Rsky involves: 129 * C57BL/6	abnormal class switch recombination	J:136224
Mir155^tm1Rsky/Mir155^tm1Rsky involves: 129 * C57BL/6	chromosomal instability	J:136224
Mir155^tm1Rsky/Mir155^tm1Rsky involves: 129/Sv * C57BL/6	abnormal cytokine secretion	J:121084
	abnormal gut-associated lymphoid tissue morphology	J:121084
	abnormal humoral immune response	J:121084
	abnormal immune system morphology	J:121084
	abnormal immune system physiology	J:121084
	abnormal Peyer's patch germinal center morphology	J:121084
	decreased interferon-gamma secretion	J:121084
	decreased interleukin-4 secretion	J:121084
	decreased spleen germinal center number	J:121084
	decreased spleen germinal center size	J:121084
	decreased tumor necrosis factor secretion	J:121084
	increased interleukin-10 secretion	J:121084

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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