Tcfl5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tcfl5
transcription factor-like 5 (basic helix-loop-helix)
MGI:2672878

14 phenotypes from 2 alleles in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Tcfl5^tm1.1Frem/Tcfl5⁺ involves: C57BL/6 * CBA	decreased litter size	J:326601
Tcfl5^tm1.1Frem/Tcfl5⁺ involves: C57BL/6 * CBA	reduced male fertility	J:326601
Tcfl5^tm1.1Frem/Tcfl5^tm1.1Frem involves: C57BL/6 * CBA	abnormal chiasmata formation	J:326601
	abnormal seminiferous tubule morphology	J:326601
	arrest of male meiosis	J:326601
	arrest of spermatogenesis	J:326601
	azoospermia	J:326601
	decreased testis weight	J:326601
	increased male germ cell apoptosis	J:326601
	male infertility	J:326601
	multinucleated giant male germ cells	J:326601
	small testis	J:326601
Tcfl5^tm1Frem/Tcfl5^tm1Frem Tg(CAG-cre/Esr1)5Amc/0 involves: C57BL/6 CBA	abnormal seminiferous tubule morphology	J:326601
	abnormal spermatid morphology	J:326601
	abnormal spermiogenesis	J:326601
	arrest of male meiosis	J:326601
	azoospermia	J:326601
	decreased testis weight	J:326601
	male infertility	J:326601
	multinucleated giant male germ cells	J:326601
	small testis	J:326601

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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