Sh3tc2 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sh3tc2
SH3 domain and tetratricopeptide repeats 2
MGI:2444417

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sh3tc2^m1J/Sh3tc2^m1J B6.Cg-Sh3tc2^m1J/GrsrRwb	abnormal Schwann cell morphology	J:229591, J:240096
	decreased grip strength	J:240096
	decreased myelin sheath thickness	J:229591, J:240096
	decreased nerve conduction velocity	J:229591, J:240096
	demyelination	J:240096
	heart block	J:240096
	normal nervous system phenotype	J:240096
	tremors	J:240096
Sh3tc2^tm1.1Rchr/Sh3tc2^tm1.1Rchr involves: 129/Sv * FVB/N	abnormal axon morphology	J:153705
	abnormal myelination	J:153705
	abnormal node of Ranvier morphology	J:153705
	decreased nerve conduction velocity	J:153705
	limb grasping	J:153705
	neurodegeneration	J:153705
	normal skeleton phenotype	J:153705
Sh3tc2^{tm1b(KOMP)Wtsi}/Sh3tc2^{tm1b(KOMP)Wtsi} C57BL/6N-Sh3tc2^{tm1b(KOMP)Wtsi}/J	decreased circulating glucose level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23