Dennd5b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dennd5b
DENN domain containing 5B
MGI:2444273

42 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dennd5b^em1(IMPC)Tcp/Dennd5b^em1(IMPC)Tcp C57BL/6N-Dennd5b^em1(IMPC)Tcp/Tcp	abnormal bone structure	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal sternum morphology	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased circulating total protein level	J:211773
	decreased circulating triglyceride level	J:211773
	decreased exploration in new environment	J:211773
	decreased heart rate	J:211773
	decreased red blood cell distribution width	J:211773
	decreased total body fat amount	J:211773
	improved glucose tolerance	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased freezing behavior	J:211773
	increased grip strength	J:211773
	increased lean body mass	J:211773
	increased leukocyte cell number	J:211773
	increased lymphocyte cell number	J:211773
	prolonged PR interval	J:211773
	prolonged QT interval	J:211773
	prolonged RR interval	J:211773
Dennd5b^em1Smgo/Dennd5b^em1Smgo involves: C57BL/6 * CBA	abnormal body mass index	J:276600
	abnormal circulating lipid level	J:276600
	abnormal digestive system physiology	J:276600
	abnormal duodenum morphology	J:276600
	abnormal intestine physiology	J:276600
	abnormal small intestine morphology	J:276600
	decreased body fat mass	J:276600
	decreased circulating HDL cholesterol level	J:276600
	decreased liver cholesterol level	J:276600
	decreased liver free fatty acids level	J:276600
	decreased susceptibility to atherosclerosis	J:276600
	decreased susceptibility to weight gain	J:276600
	distended duodenum	J:276600
	distended ileum	J:276600
	distended jejunum	J:276600
	increased circulating VLDL triglyceride level	J:276600
	increased lean body mass	J:276600
	increased small intestine length	J:276600
Dennd5b^m1Anu/Dennd5b^m1Anu C57BL/6NCrlAnu-Dennd5b^m1Anu	normal immune system phenotype	J:104190

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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