Nr1d1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nr1d1
nuclear receptor subfamily 1, group D, member 1
MGI:2444210

43 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nr1d1^em1Bwu/Nr1d1^em1Bwu involves: C57BL/6	normal digestive/alimentary phenotype	J:340220
Nr1d1^{tm1(KOMP)Vlcg}/Nr1d1^{tm1(KOMP)Vlcg} C57BL/6N-Nr1d1^{tm1(KOMP)Vlcg}/Bay	abnormal eye anterior chamber depth	J:211773
	abnormal eye morphology	J:211773
	abnormal eye posterior chamber depth	J:211773
	abnormal retina inner nuclear layer morphology	J:211773
	decreased cardiac output	J:211773
	decreased NK cell number	J:211773
	decreased thigmotaxis	J:211773
	decreased total body fat amount	J:211773
	decreased total retina thickness	J:211773
	enlarged heart	J:211773
	hyperactivity	J:211773
	increased bone mineral content	J:211773
Nr1d1^{tm1.1(KOMP)Vlcg}/Nr1d1⁺ C57BL/6N-Nr1d1^{tm1.1(KOMP)Vlcg}/Bay	unresponsive to tactile stimuli	J:211773
Nr1d1^{tm1.1(KOMP)Vlcg}/Nr1d1^{tm1.1(KOMP)Vlcg} C57BL/6N-Nr1d1^{tm1.1(KOMP)Vlcg}/Bay	preweaning lethality, incomplete penetrance	J:211773
	unresponsive to tactile stimuli	J:211773
Nr1d1^tm1.2Rev/Nr1d1^tm1.2Rev involves: BALB/cJ * C57BL/6J	postnatal lethality, incomplete penetrance	J:183855
	reduced female fertility	J:183855
	reduced male fertility	J:183855
	shortened circadian behavior period	J:183855
Nr1d1^tm1Schb/Nr1d1^tm1Schb involves: 129S2/SvPas	abnormal bile salt homeostasis	J:153064
	decreased liver cholesterol level	J:153064
	decreased liver triglyceride level	J:153064
	increased circulating HDL cholesterol level	J:153064
	increased circulating LDL cholesterol level	J:153064
Nr1d1^tm1Schb/Nr1d1^tm1Schb involves: 129S2/SvPas * C57BL/6J	advanced circadian behavior phase	J:78197
	decreased litter size	J:78197
	shortened circadian behavior period	J:78197
Nr1d1^tm1Ven/Nr1d1^tm1Ven B6.Cg-Nr1d1^tm1Ven	abnormal circadian temperature homeostasis	J:203422
	decreased susceptibility to induced hypothermia	J:203422
	decreased susceptibility to induced morbidity/mortality	J:203422
	increased adipocyte glucose uptake	J:203422
	increased body temperature	J:203422
	increased core body temperature	J:203422
	increased oxygen consumption	J:203422
Nr1d1^tm1Ven/Nr1d1^tm1Ven Not Specified	abnormal cerebellar granule cell morphology	J:60839
	abnormal cerebellar molecular layer	J:60839
	abnormal cerebellum development	J:60839
	abnormal cerebellum external granule cell layer morphology	J:60839
	abnormal cerebellum morphology	J:60839
	abnormal Purkinje cell dendrite morphology	J:60839
	abnormal Purkinje cell differentiation	J:60839
	abnormal skeletal muscle fiber type ratio	J:95758
	decreased body weight	J:95758
	increased skeletal muscle fiber size	J:95758
	reduced female fertility	J:60839

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